� MoOx NPs were successfully synthesized by the LASL method with ns pulses. � MoOx NPs possess an absorption peak located at around 840 nm. � The produced MoOx NPs show potential for Photothermal Theraphy applications. � MoOx NPs are constituted of amorphous molybdenum oxide hydrates (MoO 3 ⋅xH 2 O).