Laser in situ keratomileusis flap margin: wound healing and complications imaged by in vivo confocal microscopy

Comparison of the corneal response to laser in situ keratomileusis with flap creation using the FS15 and FS30 femtosecond lasers

“…Keratocyte activation has also been identified by confocal microscopy after microkeratome-assisted LASIK. 20,21 However, the degree of keratocyte activation and clinical haze is markedly less than that induced by PRK. Previous studies show that intra-LASIK provides more consistent flap thickness with fewer complications than traditional microkeratomes and results in better visual outcome in most patients.…”

Quantitative assessment of ophthalmic viscosurgical device retention using in vivo confocal microscopy

“…Confocal microscopy through-focusing pachymetry measurements have been used to measure photoablation depth and to follow changes in epithelial and stromal thickness following photorefractive keratectomy (PRK), 12-16 for measurement of epithelial and flap thickness following laser in situ keratomileusis (LASIK), [17][18][19] to assess changes in epithelial thickness associated with contact lens wear, 20,21 and following application of ocular irritants. 22 We are not aware of any previous reports of OVD thickness measurements made using in vivo confocal microscopy.…”

Late Onset Flap Scarring After Laser in Situ Keratomileusis

“…Histopatologic studies of corneal healing in rabbits show that the wound-healing reaction occurs at the fl ap margins, leaving the central corneal zone clear after LASIK [8]. Similar results have been described in human eyes [9,10]. The epithelium and Bowman's layer are not affected at the center of cornea, so, therefore, leads to clear visual axis.…”