Laser-induced fluorescence in medical diagnostics

Andersson‐Engels, Stefan; Johansson, Jonas; Svanberg, Katarina; Svanberg, Sune

doi:10.1117/12.17653

Cited by 14 publications

(10 citation statements)

References 44 publications

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“…Comparable studies have been performed in patients in connection with photodynamic therapy (PDT) of basal cell carcinomas and adjacent normal skin following topical application of 5-Ala in order to study PPIX build-up (Klinteberg et al 1999;Palsson et al 2003), as well as in various kinds of malignant, premalignant, and benign lesions in the head and neck region ; see also Andersson-Engels et al 2009 andCelli et al 2010 for review and Chapters 16 through 18 and 23 for more details).…”

Section: Cancer Diagnostics and Therapy Employing Porphyrinsmentioning

confidence: 99%

Oncology applications: Brain

Butte¹,

Mamelak²,

Marcu³

2014

Fluorescence Lifetime Spectroscopy and Imaging

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Section: Cancer Diagnostics and Therapy Employing Porphyrinsmentioning

confidence: 99%

Oncology applications: Brain

Butte¹,

Mamelak²,

Marcu³

2014

Fluorescence Lifetime Spectroscopy and Imaging

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“…Preliminary animal studies on PDT of intimal hyperplasia have been carried out with DHE and secondgeneration drugs, including NPe6 and BPD-MA. Fluorescence identification of abnormal tissue is an additional feature of this approach [34]. The current technology of intraarterial catheters should make possible localized intravascular drug and light delivery.…”

Section: Optical Diagnosismentioning

confidence: 99%

Photodynamic therapy

Grossweiner

1995

Journal of Laser Applications

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Photodynamic therapy (PDT) is a new treatment for solid tumors utilizing the combined action of light and a photosensitizing drug. Laser-fiber optic delivery systems make it practical to treat superficial and interstitial cancers, including malignancies of the skin, head and neck, esophagus, endobronchial tract, stomach, urinary bladder, female genital tract, and other sites. The putative action mechanism in PDT involves photochemical destruction of tumor tissue membranes mediated by singlet molecular oxygen. Light dosimetry modeling based on tissue optics is applicable for treatment planning. Related research areas include non-invasive optical diagnosis and imaging, development of new PDT drugs and light sources, and the extension of PDT methods to treatment of atherosclerotic vascular disease and blood detoxification.

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“…One of the directions is new PS for PDT, with the purpose of improving their parameters and desire to bring them nearer to the ideal [2]. Among them:…”

Section: Introductionmentioning

confidence: 99%

<title>Control system of space and time distribution of laser radiation on the basis of liquid crystal modulator for diagnostics and treatment of malignancies with the aid of photodynamic therapy method</title>

et al. 1996

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The complex for tumor diagnostics and therapy on the basis of spatial -temporary light modulators (STLM) conjugated with laser, gastroscope, videocamera on the base of CCD-matrix and computer is assembled. The choice of modulator operating mode permits us to achieve many effects, in particular, to make a contour radiating area, to provide a more intensive effect on the border of the center of pathology and to redistribute the emission intensity on the surface of pathologic tissue. The work of STLM and dependencies its characteristics from different parameters in full is described. 16 /SPIE Vol. 2728 O-8194-2104-9/96/$6.OO Downloaded From: http://proceedings.spiedigitallibrary.org/ on 06/29/2016 Terms of Use: http://spiedigitallibrary.org/ss/TermsOfUse.aspx

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Laser-induced fluorescence in medical diagnostics

Cited by 14 publications

References 44 publications

Oncology applications: Brain

Oncology applications: Brain

Photodynamic therapy

<title>Control system of space and time distribution of laser radiation on the basis of liquid crystal modulator for diagnostics and treatment of malignancies with the aid of photodynamic therapy method</title>

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