Laser-Tissue Interactions

Niemz, Markolf H.

doi:10.1007/978-3-662-04717-0

Cited by 109 publications

(125 citation statements)

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“…[4][5][6][7][8] Due to the advantage of the enhanced precision and minimized collateral tissue effects, femtosecond lasers have displaced the mechanical microkeratome as the dominant tool for LASIK flap creation in the US over the past decade. [9][10][11][12][13][14][15] Diode pumped all-solid-state femtosecond lasers are now also commonly used to perform corneal transplants [16][17][18] or being investigated to perform additional procedures, such as fs-lentotomy. [19][20][21] The iFS advanced femtosecond laser (AMO Inc., Santa Ana, California) is the most popular laser machine on the US market.…”

Section: Introductionmentioning

confidence: 99%

“…[19][20][21] The iFS advanced femtosecond laser (AMO Inc., Santa Ana, California) is the most popular laser machine on the US market. In contrast to initial systems, which operated at repetition rates of a few kilohertz, newer systems have introduced a progressive increase in repetition emission frequencies up to 15,30,60, and 150 kHz. [22][23][24] The increase in laser repetition permits the creation of a standard LASIK flap in a shorter time, which dramatically decreases the duration of the LASIK procedure.…”

Section: Introductionmentioning

confidence: 99%

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Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

et al. 2011

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Abstract.We have developed a two-dimensional computer model to predict the temperature increase of the retina during femtosecond corneal laser flap cutting. Simulating a typical clinical setting for 150-kHz iFS advanced femtosecond laser (0.8-to 1-μJ laser pulse energy and 15-s procedure time at a laser wavelength of 1053 nm), the temperature increase is 0.2• C. Calculated temperature profiles show good agreement with data obtained from ex vivo experiments using human cadaver retina. Simulation results obtained for different commercial femtosecond lasers indicate that during the laser in situ keratomileusis procedure the temperature increase of the retina is insufficient to induce damage. C 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

et al. 2011

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“…To the best of our knowledge, it is the first time that these techniques are applied in this field: analytical models constitute the traditional approach for the analysis of the interaction of the laser with the tissue [1]. With respect to existing approaches, our modeling methodology explicitly considers typical laser parameters used by clinicians during an intervention, (i.e.…”

Section: Discussionmentioning

confidence: 99%

Conclusions and Future Research Directions

Fichera

2016

Springer Theses

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This chapter presents a conclusion to the work described in this doctoral dissertation. The main contributions are summarized, followed by some suggestions regarding future directions of research related to this work. Concluding RemarksThe main thrust of this thesis is to enable the automatic monitoring of laser-induced changes on tissues during robot-assisted laser microsurgery. Two types of effects were studied: thermal (tissue temperature variation) and mechanical (creation of the incision crater). Surgeon control of these effects is crucial to surgical outcomes, yet these are difficult to perceive and require a significant amount of cognitive acuity. Computer and robot-assisted surgical systems should extend the surgeon performance beyond the limitations of human possibilities, not just in terms of what the surgeon is able to do, but also in the perception of relevant processes that are difficult or impossible to sense. Drawing on these practical problems, this doctoral dissertation focused on the development of models capable of describing the changes induced by surgical lasers on soft tissues, under the condition that these models must be compatible with use in a real surgical setting.This dissertation successfully demonstrates the applicability of statistical learning methods to model the laser incision process during laser microsurgery. To the best of our knowledge, it is the first time that these techniques are applied in this field: analytical models constitute the traditional approach for the analysis of the interaction of the laser with the tissue [1]. With respect to existing approaches, our modeling methodology explicitly considers typical laser parameters used by clinicians during an intervention, (i.e. power, scanning frequency, energy delivery mode, incision length and laser exposure time), thus producing models that are straightforward to use in a surgical scenario either for monitoring or control applications.

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“…At normal incidence the reflectance of a surface separating air and water is about 2% [1,2], but in several cases the reflectance can be important, with values that cannot be neglected; in these cases proper eye protection when using lasers is needed.…”

Section: Basic Phenomena Regarding Light and Tissuesmentioning

confidence: 99%

Mathematical Methods in Biomedical Optics

Gabriela

2013

ISRN Biomedical Engineering

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This paper presents a review of the phenomena regarding light-tissue interactions, especially absorption and scattering. The most important mathematical approaches for modeling the light transport in tissues and their domain of application: “first-order scattering,” “Kubelka-Munk theory,” “diffusion approximation,” “Monte Carlo simulation,” “inverse adding-doubling” and “finite element method” are briefly described.

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Laser-Tissue Interactions

Cited by 109 publications

References 0 publications

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Conclusions and Future Research Directions

Mathematical Methods in Biomedical Optics

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