Laser treatment in hemangiomas and vascular malformations

Poetke, M.; Berlien, H.-P.

doi:10.1016/j.mla.2005.03.008

Cited by 18 publications

(10 citation statements)

References 22 publications

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“…In the literature, the use of laser and pulsed light for superficial lesions has been associated with considerable success rates. 29 The use of imiquimod is a promising therapeutic option, principally for small to medium-sized lesions that are not excessively deep. 19,20 The two patients (2%) treated with this medication achieved a fast response that resulted in partial cure in the case of the patient with a paranasal lesion and complete cure in the patient with a lesion on his lower eyelid.…”

Section: Discussionmentioning

confidence: 99%

Abordagem terapêutica dos hemangiomas cutâneos na infância

A¹,

Soares²,

Júnior³

et al. 2010

An. Bras. Dermatol.

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BACKGROUND: Hemangiomas are benign, self-involuting tumors of endothelial cells that are common in childhood. OBJECTIVES: To evaluate the treatment of 122 patients with skin hemangiomas treated at a teaching hospital in Brasilia, Brazil between March 2000 and December 2006. MATERIAL AND METHODS: Data were collected from the patients' medical records and questionnaires were applied to the children's parents. Variables analyzed were: gender, pre-and perinatal factors, clinical characteristics of the lesions, type of treatment and outcome. RESULTS: A male-to-female ratio of 1.5:1 was found. In 42 patients, hemangiomas were superficial, while in 13 cases they were deep and in 67 patients lesions were mixed. In 7 patients, the lesions were associated with syndromes. In 79 patients, hemangiomas were in the cephalic region. Of the 122 patients, 98 were submitted to one single treatment, while 24 required multiple forms of treatment. In the first group, expectant management was the conduct in 38 patients, compression in 3 cases, systemic corticotherapy in 18 patients, intralesional corticotherapy in 13, topical steroids in 4 cases, conventional surgery in 12 patients, cryosurgery in 7, pulsed light in one case and imiquimod in 2 patients. In the second group of 24 patients submitted to multiple treatment modalities, 15 required two types of treatment and 9 needed three or more. CONCLUSIONS: The data obtained in this study were in agreement with results in the literature with respect to gender and the site of the lesions. The incidence of hemangiomas present at birth was higher than rates published in the literature. The therapeutical results obtained were comparable with data from other published studies. Identification of hemangiomas that require treatment, as well as the right moment for intervention and the best therapeutic option for each case, are factors that need to be taken into consideration. Keywords: corticosteroids; combined therapy; cryosurgery; outcome of therapeutic interventions; general surgery; hemangioma; therapeutics Resumo: FUNDAMENTOS: Hemangioma é um tumor benigno de células endoteliais comum na infância e de involução espontânea. OBJETIVO: Avaliar os tratamentos utilizados em 122 pacientes com hemangiomas cutâ-neos, tratados no Hospital Universitário de Brasília, de março de 2000 a dezembro de 2006. MÉTODOS: Utilizou-se coleta de dados em prontuários e aplicação de questionários aos pais. Foram analisados gênero, fatores pré-natais e perinatais, características clínicas, tipo de tratamento e resultados. RESULTADOS: A razão de sexo (F: M) foi de 1,5:1. 42, em pacientes que apresentavam hemangiomas superficiais, 13 profundos e 67 mistos; em 7 pacientes, havia associação com síndromes. Em 79 pacientes, localizavam-se no polo cefálico. Já em 98/122 dos pacientes, foram submetidos a tratamento único e 24/122 a múltiplos. No primeiro grupo, foi utilizada conduta expectante em 38 pacientes, compressão em 3, corticoide sistêmico em 18, corticoide intralesional em 13, corticoide tópico em 4, cir...

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Section: Discussionmentioning

confidence: 99%

Abordagem terapêutica dos hemangiomas cutâneos na infância

A¹,

Soares²,

Júnior³

et al. 2010

An. Bras. Dermatol.

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show abstract

“…В современной литературе описаны различ-ные методики лечения гемангиом, такие как химио-терапия с использованием препаратов винкристин и циклофосфамид [12][13][14], ингибиторов ангиогенеза (интерферон альфа2a [9,[15][16][17]), стероидов [15,17], радио- [12,18,19] или криотерапии [13,16,[20][21][22], терапевтической эмболизации [9,16,18,23]; при-менение лазеров [5,16]; радикальное хирургическое лечение [22,24].…”

Section: классификацияunclassified

“…Гемангиомы -наиболее распространенные добро-качественные сосудистые опухоли, встречающиеся у 1,5-3% новорожденных и 10-12% детей первого года жизни [1][2][3][4][5][6]. Для гемангиом характерен быстрый рост в период новорожденности с последующим его замедлением и дальнейшей инволюцией после одного года жизни [1,3,4,6].…”

Section: Introductionunclassified

“…При регрессии яркость гемангиомы уменьшается, на ней появляются участки беловатого цвета, прекра-щается периферический рост. Через 6-8 мес ангиома представляет гладкое невозвышающееся над кожей беловато-розовое пятно, кожа над которым подвергает-ся атрофии, а к 3-4-му году жизни остается небольшой депигментированный участок кожи [1][2][3][4][5][6].…”

Section: Introductionunclassified

See 1 more Smart Citation

Use of Propranol for Treating Complicated Hemangiomas in Children

Кучеров¹,

Жиркова²,

Рехвиашвили³

et al. 2014

Pediatr. farmakol.

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“…Percutaneous interstitial laser therapy of the liver mass is known from studies about the treatment of colorectal liver metastasis [9,10]. Some papers are related to the interstitial laser treatment of congenital vascular disease (CVD), showing that ILT provides denaturation of tissue and subsequent obstruction of vessels [11][12][13][14]. Sometimes the ILT procedure can be very helpful even in benign, life-threatening disorders such as infantile liver hemangiomatosis.…”

Section: Introductionmentioning

confidence: 99%