Laser treatment of cutaneous angiokeratomas: A systematic review

Nguyen, John D.; Chapman, Lance W.; Korta, Dorota Z.; Zachary, Christopher B.

doi:10.1111/dth.12558

Cited by 19 publications

(14 citation statements)

References 32 publications

(54 reference statements)

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“…The incidence of scrotal angiokeratomas remains to be determined. Local destructive methods, including lasers (Table 2 ) [ 13 , 14 , 22 – 31 ], have traditionally been used to treat angiokeratoma of the scrotum [ 1 – 4 , 6 , 12 – 14 , 21 – 31 ].…”

Section: Discussionmentioning

confidence: 99%

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A Case Report of Scrotal Rejuvenation: Laser Treatment of Angiokeratomas of the Scrotum

Cohen¹

2018

Dermatol Ther (Heidelb)

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Scrotal rejuvenation encompasses not only the functional quality but also the aesthetic appearance of the scrotum. It includes medical therapy and procedural interventions to improve scrotal conditions that require morphologic restoration and/or aesthetic alteration. Rejuvenation of the scrotum may be appropriate for aging-related and non-aging-related changes concerning the hair (alopecia and hypertrichosis), the morphology (laxity and wrinkles), and/or the vascularity (angiokeratoma) of the scrotum. Angiokeratomas—typically small, asymptomatic, purple papules—may occur on the scrotum. However, these benign vascular lesions may be of cosmetic concern to the affected individuals; in addition, the angiokeratomas can become an issue of medical importance if they begin to bleed. Multiple locally destructive modalities are available for the treatment of scrotal angiokeratomas; indeed, several lasers have effectively been used to treat angiokeratomas of the scrotum. A 70-year-old man with numerous scrotal angiokeratomas experienced scrotal bleeding in the absence of prior trauma to the area or sexual activity. He presented for treatment to prevent future episodes of spontaneous bleeding from his scrotal angiokeratomas, but he also had not liked the aesthetic appearance of the previously asymptomatic angiokeratomas on his scrotum. His angiokeratomas were successfully treated with three sequential 532-nm potassium titanyl phosphate (KTP) laser sessions, which led to not only functional but also cosmetic improvement of his scrotum. In conclusion, men can develop scrotal changes due to either intrinsic (aging) or extrinsic (trauma) causes, but nonsurgical interventions and surgical procedures are available for the management of these conditions in individuals who desire to rejuvenate their scrotum.

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Section: Discussionmentioning

confidence: 99%

“…The 532-nm wavelength is produced by placing a KTP crystal in the path of a 1064-nm Nd:YAG laser beam, which results in a frequency-doubled 532-nm wavelength, which is absorbed well by oxyhemoglobin. The laser allows contact cooling through a sapphire window [ 22 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Scrotal Rejuvenation: Laser Treatment of Angiokeratomas of the Scrotum

Cohen¹

2018

Dermatol Ther (Heidelb)

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“…Cryotherapy, electrosurgery, excision, laser surgery and sclerotherapy have all been successfully used to treat angiokeratomas. Indeed, several of these techniques have been used in men with PEAKERs [54][55][56].…”

Section: Treatmentmentioning

confidence: 99%

Penile Angiokeratomas (PEAKERs) Revisited: A Comprehensive Review

Cohen

Celano

2020

Dermatol Ther (Heidelb)

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Angiokeratomas are benign vascular lesions. Genital angiokeratomas, also referred to as Fordyce angiokeratomas, usually occur on the scrotum in men and the vulva in women. Penile angiokeratoma (PEAKER) is a subtype of genital angiokeratoma in men; clitoral angiokeratoma (CLANKER) is its embryologic analog in women. The PubMed database was used to search the following words: angiokeratoma, clitoris, genital, peaker, penile, penis, rejuvenation, scrotal, scrotum and vulva. The relevant papers and references cited in those papers that were generated by the search were reviewed. The purpose of this article is to summarize the features of PEAKERs. PEAKERs have been described in 54 men. They usually appeared in younger men and had been present for a mean duration of 4 years prior to the individual seeking medical attention. Only 39% of the men had angiokeratoma-associated symptoms:

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“…Angiokeratomas are benign vascular neoplasms that arise as solitary or multiple lesions, most commonly observed as hyperkeratotic, red to black papules or plaques [1][2][3]. Histologically, there is marked dilation of the papillary capillaries.…”

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confidence: 99%

Topical sirolimus for treatment of a solitary angiokeratoma

Camacho

Scott

DeKlotz

2020

Dermatologic Therapy

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Angiokeratomas are benign vascular neoplasms that arise as solitary or multiple lesions, most commonly treated with excision, electrodessication, cryotherapy, or laser therapies. This case presents a young female whose solitary angiokeratoma was treated with topical 1% sirolimus cream, improving the appearance, symptoms, and size of the lesion. Topical sirolimus cream may be a noninvasive treatment option for angiokeratomas with fewer risks than standard therapy that may be feasible and preferable for some patients.

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Laser treatment of cutaneous angiokeratomas: A systematic review

Cited by 19 publications

References 32 publications

A Case Report of Scrotal Rejuvenation: Laser Treatment of Angiokeratomas of the Scrotum

A Case Report of Scrotal Rejuvenation: Laser Treatment of Angiokeratomas of the Scrotum

Penile Angiokeratomas (PEAKERs) Revisited: A Comprehensive Review

Topical sirolimus for treatment of a solitary angiokeratoma

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