Laser Treatment of Hereditary Multiple Glomus Tumors

Barnes, Louise; Estes, Stephen A.

doi:10.1111/j.1524-4725.1986.tb02130.x

Cited by 63 publications

(36 citation statements)

References 16 publications

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“…Some studies have shown good results using sclerotherapy with tetradecyl sulfate, polidocanol and hypertonic saline in the treatment of multiple GVMs on the limbs . Ablation with argon, carbon‐dioxide or pulsed dye laser can also sometimes help reduce the thickness and symptoms of GVMs …”

Section: Discussionmentioning

confidence: 99%

Large plaque-like glomangioma in a patient with multiple glomus tumours: review of imaging and histology

Tony

Hauxwell²,

Nair

et al. 2013

Clin Exp Dermatol

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SummaryGlomus tumours are benign tumours of the temperature-sensitive neuromyoarterial glomus body, present within the dermis, which are most commonly seen as solitary subungual lesions on the arms. Multiple glomus tumours or glomangiomas are a less common subtype of extradigital glomus tumours, which very rarely present as large plaque-like dermal lesions. Glomangiomas do not often show the classic triad of symptoms associated with glomus tumours, namely: pain, point tenderness on compression, and temperature sensitivity. As a result of this and of their atypical morphology, they can often be misdiagnosed as vascular malformations (VMs), resulting in delayed diagnosis and inappropriate treatment. We report a 29-year-old man with multiple extradigital glomus tumours that had been present since childhood, with the lesion on the patient's leg being the largest plaque-like glomangioma yet reported, to our knowledge. Spectral greyscale and Doppler shift ultrasonography showed multiple, tubulonodular, ectatic, noncompressible, vascular structures with aberrant flow within the thickened dermis. Using magnetic resonance imaging, low to intermediate signal was seen on T1-weighted images and high signal on T2-weighted images, and there was florid enhancement with gadolinium, with no evidence of extension into muscle or bone. Histology showed abnormal, dilated, thin-walled, vascular channels lined with multiple layers of glomus cells, confirming the diagnosis of a glomangioma. We discuss imaging techniques for plaque-like glomangiomas, and review the clinical, radiological and histological characteristics that help differentiate them from other superficial VMs.

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Section: Discussionmentioning

confidence: 99%

Large plaque-like glomangioma in a patient with multiple glomus tumours: review of imaging and histology

Tony

Hauxwell²,

Nair

et al. 2013

Clin Exp Dermatol

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“…Successful treatment of multiple glomangiomas has been reported with electron beam irradiation, sclerotherapy, and laser therapy (ablative or pulse dye). [135][136][137][138][139][140] Malignant glomus tumors (also known as glomangiosarcomas) are rare neoplasms, and some authors even doubt that such lesions exist, the most controversial issue being the recognition and acceptance of those in which no benign component is present. In addition to the soft tissue, malignant glomus tumors have been reported in a variety of sites, including skin, bone, bladder, central nervous system, lung, and gastrointestinal tract.…”

Section: Glomus Tumors and Glomangiosarcomasmentioning

confidence: 99%

Perivascular Cell Neoplasms

Sangüeza¹,

Requena²,

Walsh³

2008

Pathology Case Reviews

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Originally, the family of perivascular neoplasms included hemangiopericytomas and glomus tumors. However, tumors once thought to be hemangiopericytomas now have mostly been reclassified into more specific entities. Currently, we recognize a category of mesenchymal tumors that have perivascular localization and myogenic differentiation, which includes PEComas, myofibromas and myopericytomas, and glomus tumors (including malignant cases). Such tumors have broadened the spectrum of vascular neoplasms.

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“…Malignant change has not been reported in multiple glomus tumours and therefore treatment is essentially symptomatic. Traditionally laser therapy has used the argon and carbon dioxide lasers, which are ablative in nature 7 . We used pulsed dye laser because of the large number of ectatic vessels in the lesion.…”

Section: Reportmentioning

confidence: 99%

Complete pain relief following treatment of a glomangiomyoma with the pulsed dye laser

Antony

Cliff

Cowley

2003

Clinical and Experimental Dermatology

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Hereditary multiple glomus tumours constitute an autosomal dominant skin disease which is known to demonstrate cutaneous mosaicism typified by type 1 and 2 segmental arrangements. We report a patient with type 2 segmental multiple glomangiomyomas who was disturbed by the pain of her lesions. A symptomatic lesion was successfully treated with the pulsed dye laser and to date there has been no recurrence of the pain. Possible explanations for the clinical response are discussed.

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Laser Treatment of Hereditary Multiple Glomus Tumors

Cited by 63 publications

References 16 publications

Large plaque-like glomangioma in a patient with multiple glomus tumours: review of imaging and histology

Large plaque-like glomangioma in a patient with multiple glomus tumours: review of imaging and histology

Perivascular Cell Neoplasms

Complete pain relief following treatment of a glomangiomyoma with the pulsed dye laser

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