2017
DOI: 10.1088/1361-6439/aa9962
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Laser welding of pre-functionalized glass substrates: a fabrication and chemical stability study

Abstract: Low-temperature bonding of glass substrates is of great interest in the field of microfluidic-based biosensing, and we study how laser welding could be used for this. This technology allows for the modification of glass channels with temperature-sensitive materials prior to bonding. We study the effects of the welding process by investigation of the thermal degradation of a biotin monolayer and whether it retains the ability to conjugate with fluorescently-labelled streptavidin.

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Cited by 2 publications
(2 citation statements)
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“…Femtosecond laser processing of glass has attracted huge attention in recent years for applications utilizing glass such as photonics, displays, and optoelectronics [8,9]. It has revolutionized glass micromachining and glass-to-glass bonding to allow simple, rapid, and stable fabrication and packaging processes [10,11,12,13,14,15,16,17,18,19]. Femtosecond laser processing has also reduced the fabrication complexity as it can be utilized for both the formation of micro-patterns and the packaging of a glass chip.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…Femtosecond laser processing of glass has attracted huge attention in recent years for applications utilizing glass such as photonics, displays, and optoelectronics [8,9]. It has revolutionized glass micromachining and glass-to-glass bonding to allow simple, rapid, and stable fabrication and packaging processes [10,11,12,13,14,15,16,17,18,19]. Femtosecond laser processing has also reduced the fabrication complexity as it can be utilized for both the formation of micro-patterns and the packaging of a glass chip.…”
Section: Introductionmentioning
confidence: 99%
“…Third, it has higher bonding strength than other bonding methods [16,18,20,21]. Although there is a lack of standardization and evaluation protocol of welding strength measurements thus far, a number of prior studies have already proven that femtosecond laser direct welding shows superior bonding strength compared with conventional bonding methods (e.g., shear stress measurement, three-point bending test, fracture strength, and simple leak check) [19,21,22,23,24].…”
Section: Introductionmentioning
confidence: 99%