Lassa fever: History, causes, effects, and reduction strategies

Tewogbola, Promise; Aung, Norah

doi:10.14202/ijoh.2020.95-98

Cited by 9 publications

(7 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tewogbola & Aung in 2020 [3] said Lassa fever is a disease that is not popular worldwide, mostly due to the incapacity of the primary vector of the Lassa virus; rat to breed in temperate regions, hence it is confined to where it is conducive for it.…”

Section: Introductionmentioning

confidence: 99%

The Role of Weather in the Spread of Lassa Fever in Parts of Northern Nigeria

Nchom

Abubakar

Arimoro

et al. 2021

IJTDH

View full text Add to dashboard Cite

This study employed multiple regression analysis to evaluate the impact of weather variables (relative humidity, rainfall amount and maximum temperature) on the reported number of Lassa fever cases and to assess the strength of relationship between same for thirteen states in northern Nigeria (Adamawa, Bauchi, Jigawa, Borno, Kaduna, Katsina, Kano, Kebbi, Sokoto, Taraba, Yobe, Zamfara and Gombe states) over a five-year period (2016-2020). Secondary data on Lassa fever disease and weather variables were described on a weekly basis from the data base of the Nigeria Centre for disease control (NCDC) as well as weather variables from the National Aeronautics Space Administration, U.S.A. (NASA). The study seeks to establish the role of weather in the occurrence of Lassa fever in parts of Northern Nigeria and also to evaluate the impact of these weather variables on the occurrence of the disease. The study reveals that these weather variables accounted for 70% (r2=0.70) of the cases of Lassa fever reported in Northern Nigeria. It occurred all year round but cases peaked during the dry months, from December to March where relative humidity is low and rainfall amount small. At confidence level of 0.05, there was a significant (p=0.000) strong positive correlation of r=0.83 between Lassa fever cases and weather variables. Of the three weather parameters, maximum temperature had a weak positive and insignificant (p=0.3) relationship with Lassa fever while relative humidity and rainfall had strong and moderate negative relationships of r = -0.7 and r = -0.5 respectively which were both significant at (r2=0.000). In conclusion, there is need to cultivate sufficient preparedness strategies in order to cope with the burden to ensure general wellbeing of people resident in these affected areas using these weather parameters.

show abstract

Section: Introductionmentioning

confidence: 99%

The Role of Weather in the Spread of Lassa Fever in Parts of Northern Nigeria

Nchom

Abubakar

Arimoro

et al. 2021

IJTDH

View full text Add to dashboard Cite

show abstract

“…The case reported here was admitted to the ETC with symptoms that included those in the EVD case definition. 11 Additionally, he presented a respiratory distress syndrome that is common in Lassa fever (up to 20% of cases) 12 , 13 as well as in COVID-19. 14 Laboratory testing showed liver and kidney failure, which directed the clinical management team to conduct further testing as early identification of Lassa fever is one of the critical points for maximizing the benefit of further available care such as antiviral therapy.…”

Section: Discussionmentioning

confidence: 99%

Case Report: COVID-19 and Lassa Fever Coinfection in an Ebola Suspected Patient in Guinea

Keïta

Chérif

Sivahera

et al. 2022

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

In this case report, we describe a clinical presentation and therapeutic history of a unique case diagnosed with Lassa fever and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 23-year-old man from Yomou prefecture in southeast Guinea identified with suspected Ebola Virus Disease (EVD) in the midst of an ongoing outbreak of that disease in the same region. On May 3, 2021, he was admitted to the Nzérékoré Epidemic disease treatment center where his clinical condition deteriorated significantly. Laboratory testing performed on the same day reveals a negative EVD polymerase chain reaction (PCR). Three days later, the patient was tested positive for SARS-CoV-2 and Lassa fever by reverse transcriptase PCR (RT-PCR) assays. Laboratory examination also indicated severe hematological and biochemical deteriorations in the patient. This case substantiates the need for systematic differential diagnosis during epidemic-prone disease outbreaks to better manage severely unwell patients.

show abstract

“…As with all evolutionary processes, it is expected that some people in endemic areas might develop some form of immunological response that may trigger resistance with time. Tewogbola and Aung [96] suggest that the Yoruba ethnic group of Nigeria to some extent has formed resistance to LASV when compared to other endemic areas. Klitting, et al [27] also predict that in the next few decades, LASV may extend beyond its current geographical borders as its predecessor Ebola virus if it is introduced to a new habitat that is fitting for its needs.…”

Section: Sustainable Management Strategies For Lassa Fever In Nigeriamentioning

confidence: 99%