When young people come to harm in extra-familial contexts, professionals may move them a distance from their home community to protect them, and in doing so disrupt relationships in which they have encountered harm. However, relocations can also fracture young people’s protective relationships with family, peers, and professionals; relationships that have been positioned as targets for intervention in cases of extra-familial harm. The extent to which these relationships are considered during relocations is under-explored. Utilising semi-structured interviews with 16 social work professionals in England and Wales, we assessed their accounts of using relationships prior to, during, and following relocations in cases of extra-familial harm. Three themes emerged: using relationships during relocations to provide consistency, to collaborate, and to create safety. Professional accounts prioritised young people’s relationships with practitioners, over relationships with families, peers, and their wider communities, when using/seeking opportunities to offer consistency and to collaborate on safety plans. They also depicted a struggle to engage with the complex web of family, peer, and community relationships associated to young people’s protection in both their home communities and those they had been moved to; relationships that were critical for creating safety. Implications for practice and future research are discussed, highlighting the potential merits of offering integrated research and practice frameworks that hold together young people’s relationships with families, peers, communities, and professionals, in response to extra-familial harm.