Late Emergence of Contrast-enhancing Fat Necrosis Mimicking Tumor Seeding after Renal Cryoablation

Durack, Jeremy C.; Richioud, Bertrand; Lyon, James; Solomon, Stephen B.

doi:10.1016/j.jvir.2013.07.006

Cited by 14 publications

(5 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our report describes a case of tumefactive fat necrosis with multinucleate GC reaction presented as a distinct mass in the perinephric tissue concerning for cancer recurrence. Our finding of tumefactive fat necrosis following cryoablation of a renal mass has been similarly reported by Durack et al [6]. They describe 2 patients who presented with RCC, underwent cryoablation, and developed what looked like RCC recurrence.…”

Section: Discussionsupporting

confidence: 87%

“…They describe 2 patients who presented with RCC, underwent cryoablation, and developed what looked like RCC recurrence. The patients underwent biopsy which confirmed both lesions as benign soft-tissue nodules with fat necrosis, fibrosis, inflammation, and histiocytes present [6]. The case demonstrates the benefit of biopsy, when possible, to avoid unnecessary excision of benign renal masses.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Tumefactive Fat Necrosis with Multinucleate Giant Cell Reaction Mimicking Recurrent Renal Cell Carcinoma following Percutaneous Renal Cryoablation

Kahn

Thiel

2019

Case Reports in Urology

View full text Add to dashboard Cite

Multinucleate Giant Cell (GC) reaction is a biological response that occurs secondary to infection, an implanted foreign body, tissue injury, or inflammation. In rare instances GC reactions have been reported following tissue ablation. Multinucleate GC reactions and tumefactive fat necrosis both have the ability to mimic cancer recurrence or metastasis and can appear as enhancing masses. We discuss a case of a surgically resected retroperitoneal perinephric mass thought to be recurrent renal cell carcinoma (RCC) that was pathologically confirmed as tumefactive fat necrosis with multinucleate GC reaction 2 years following percutaneous cryoablation of a small renal mass.

show abstract

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Tumefactive Fat Necrosis with Multinucleate Giant Cell Reaction Mimicking Recurrent Renal Cell Carcinoma following Percutaneous Renal Cryoablation

Kahn

Thiel

2019

Case Reports in Urology

View full text Add to dashboard Cite

show abstract

“…Dystrophic calcification is a common late finding and may occur within the ablation zone [ 9 22 ] ( Fig. 7 ).…”

Section: Assessing Post-ablation Enhancementmentioning

confidence: 99%

Assessment of Local Tumor Progression After Image-Guided Thermal Ablation for Renal Cell Carcinoma

Park

2024

Korean J Radiol

View full text Add to dashboard Cite

Focal enhancement typically suggests local tumor progression (LTP) after renal cell carcinoma is percutaneously ablated. However, evaluating findings that are false positive or negative of LTP is less familiar to radiologists who have little experience with renal ablation. Various imaging features are encountered during and after thermal ablation. Ablation procedures and previous follow-up imaging should be reviewed before determining if there is LTP. Previous studies have focused on detecting the presence or absence of focal enhancement within the ablation zone. Therefore, various diagnostic pitfalls can be experienced using computed tomography or magnetic resonance imaging examinations. This review aimed to assess how to read images during or after ablation procedures, recognize imaging features of LTP and determine factors that influence LTP.

show abstract

“…Invagination of fat in the scar is rare and occurs later [ 67 ]. Renal ablation zone soft-tissue nodules from fat necrosis can appear long after ablation, enhance with contrast medium, mimic applicator tract or ablation zone tumor seeding, and may require biopsy for confirmation of benignity [ 69 ]. If necessary, biopsies should be performed 6 months after ablation and should not be systematic, based on a case-by-case discussion based on imaging findings [ 60 , 69 ].…”

Section: B Follow-up After Thermal Ablation For Renal Cancermentioning

confidence: 99%

Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice

et al. 2020

Self Cite

View full text Add to dashboard Cite

Interventional radiology plays an important and increasing role in cancer treatment. Follow-up is important to be able to assess treatment success and detect locoregional and distant recurrence and recommendations for follow-up are needed. At ECIO 2018, a joint ECIO-ESOI session was organized to establish follow-up recommendations for oncologic intervention in liver, renal, and lung cancer. Treatments included thermal ablation, TACE, and TARE. In total five topics were evaluated: ablation in colorectal liver metastases (CRLM), TARE in CRLM, TACE and TARE in HCC, ablation in renal cancer, and ablation in lung cancer. Evaluated modalities were FDG-PET-CT, CT, MRI, and (contrast-enhanced) ultrasound. Prior to the session, five experts were selected and performed a systematic review and presented statements, which were voted on in a telephone conference prior to the meeting by all panelists. These statements were presented and discussed at the ECIO-ESOI session at ECIO 2018. This paper presents the recommendations that followed from these initiatives. Based on expert opinions and the available evidence, follow-up schedules were proposed for liver cancer, renal cancer, and lung cancer. FDG-PET-CT, CT, and MRI are the recommended modalities, but one should beware of false-positive signs of residual tumor or recurrence due to inflammation early after the intervention. There is a need for prospective preferably multicenter studies to validate new techniques and new response criteria. This paper presents recommendations that can be used in clinical practice to perform the follow-up of patients with liver, lung, and renal cancer who were treated with interventional locoregional therapies.

show abstract

Late Emergence of Contrast-enhancing Fat Necrosis Mimicking Tumor Seeding after Renal Cryoablation

Cited by 14 publications

References 14 publications

Tumefactive Fat Necrosis with Multinucleate Giant Cell Reaction Mimicking Recurrent Renal Cell Carcinoma following Percutaneous Renal Cryoablation

Tumefactive Fat Necrosis with Multinucleate Giant Cell Reaction Mimicking Recurrent Renal Cell Carcinoma following Percutaneous Renal Cryoablation

Assessment of Local Tumor Progression After Image-Guided Thermal Ablation for Renal Cell Carcinoma

Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice

Contact Info

Product

Resources

About