“…[1] There are various factors held responsible for the spontaneous migration of catheter tip such as, “jet effect” of drug injection, increased intrathoracic, intra-abdominal pressures, and mechanical ventilation. [12] The CVC catheter tip placement in various venous tributary systems and structures such as left subclavian vein, left internal mammary vein, azygos vein, hemiazygos vein, lateral thoracic vein, inferior thyroid vein, left superior intercostal vein, thymic vein, pleural cavity, and the jugular foramen is known. [3] CVC malpositioning into left subclavian through right subclavian is also been described in literature.…”