Late onset rheumatoid arthritis: Clinical and laboratory comparisons with younger onset patients

Türkçapar, Nuran; Demir, Özgür; Atlı, Teslime; Kopuk, Murat; Turgay, Murat; Kınıklı, Gülay; Duman, Murat

doi:10.1016/j.archger.2005.07.003

Cited by 81 publications

(51 citation statements)

References 9 publications

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“…Differences were tested using the Mann-Whitney U test. monly present with severe illness, including arthritic and constitutional symptoms leading to transient or permanent immobility (8). Our data support this observation, suggesting that EORA patients have even higher inflammatory scores at sonographic than at clinical examination.…”

Section: Discussionsupporting

confidence: 80%

“…In previous RA cohorts, a similar distribution of clinical and sonographic findings was reported (11). It can be assumed that the sonographic patterns of EORA and YORA patients are different, if large joints, particularly shoulders, are examined (8). Besides, involvement of metatarsophalangeal joints is often asymptomatic in RA and no data exist on the prevalence of ultrasound findings at these sites in elderly RA patients.…”

Section: Discussionmentioning

confidence: 83%

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Elderly‐ versus younger‐onset rheumatoid arthritis: Higher levels of ultrasound‐detected inflammation despite comparable clinical disease activity

Dejaco

Duftner

Wipfler-Freißmuth

et al. 2013

Arthritis Care & Research

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Objective. To compare ultrasound-verified joint inflammation between elderly-onset rheumatoid arthritis (EORA) and younger-onset rheumatoid arthritis (YORA) patients. Methods. We conducted a retrospective analysis of 145 consecutive rheumatoid arthritis patients routinely assessed by sonography of wrists, metacarpophalangeal joints, and proximal interphalangeal joints, including semiquantitative scoring of synovial hypertrophy/effusion (SH/E) and power Doppler (PD) signals. Global ultrasound (GU) scores were calculated adding SH/E and PD results. EORA was defined by disease onset at age >60 years. Number of tender joints and swollen joints, global assessment of disease activity by physician or patient, Disease Activity Score in 28 joints (DAS28), Clinical Disease Activity Index (CDAI), and Simplified Disease Activity Index (SDAI) scores were recorded. Respective values for disease activity were accounted for in group comparisons using SPSS statistical software (version 18.0). Results. Seventy patients were diagnosed with EORA (mean

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 83%

Elderly‐ versus younger‐onset rheumatoid arthritis: Higher levels of ultrasound‐detected inflammation despite comparable clinical disease activity

Dejaco

Duftner

Wipfler-Freißmuth

et al. 2013

Arthritis Care & Research

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“…Recent studies have differentiated between the clinical and laboratory features of EORA and LORA, and although there are some contradictions involving various parameters, such as morning stiffness, the presence of autoantibodies and the anti-CCP levels are similar. [2][3][4][5] As previously mentioned, there are clinical differences between LORA and EORA. For example, the majority of LORA patients have an acute onset, and instead of classical joint involvement, mostly large joints like the shoulders are initially affected.…”

mentioning

confidence: 80%

An Overview of Late-onset Rheumatoid Arthritis

Evcik

2013

Turk J Rheumatol

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“…PMR involves large joints and is often seen in females. In contrast, small joints are affected without bony erosion and male predominance is seen in patients with RS3PE (Table 2) 40,47,48 .…”

Section: Differential Diagnosismentioning

confidence: 99%

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome

Gökçen¹,

Kozanoğlu²

2017

Cukurova Medical Journal (Çukurova Üniversitesi Tıp Fakültesi Dergisi)

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AbstractÖz Remitting seronegative symmetrical synovitis with pitting edema is a rare rheumatological disorder that presents with symmetrical hand and/or foot edema resembling rheumatoid arthritis. It is generally seen in male patients in older age, but atypical cases in different age groups have been documented. Although no clear mechanism has been described, certain genetic and environmental factors have been suggested for etiopathogenesis. Medical treatment is mainly focused on glucocorticoid therapy. This article aims to discuss the Remitting seronegative symmetrical synovitis with pitting edema syndrome and to review the current literature.Tekrarlayıcı seronegatif pitting ödemli simetrik sinovit sendromu, romatoid artriti andıran simetrik el ve/veya ayak ödemi ile prezente olan nadir görülen bir hastalıktır. Genellikle ileri yaş erkek hastalarda görülür fakat farklı yaş gruplarında görülen atipik vakalar da bulunmaktadır. Net bir mekanizma tanımlanmamış olmasına rağmen, etiyopatogenezde belli genetik ve çevresel faktörler öne sürülmektedir. Tedavi, esasen glukokortikoid tedavisi üzerine odaklanmaktadır. Bu derlemede Tekrarlayıcı seronegatif pitting ödemli simetrik sinovit sendromunun tartışılması ve literatürün gözden geçirilmesi amaçlanmıştır.

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Late onset rheumatoid arthritis: Clinical and laboratory comparisons with younger onset patients

Cited by 81 publications

References 9 publications

Elderly‐ versus younger‐onset rheumatoid arthritis: Higher levels of ultrasound‐detected inflammation despite comparable clinical disease activity

Elderly‐ versus younger‐onset rheumatoid arthritis: Higher levels of ultrasound‐detected inflammation despite comparable clinical disease activity

An Overview of Late-onset Rheumatoid Arthritis

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome

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