Late preterm and early term children: the early years at school

Marlow, Neil

doi:10.1136/archdischild-2014-306557

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…In addition, they are exposed to a wider spectrum of brain lesions common to both most premature and more mature babies as they can develop not only germinal matrix-intraventricular hemorrhage (GMH-IVH) and cystic periventricular leukomalacia (cPVL) but also arterial/venous stroke [ 9 ], hypoxic-ischemic encephalopathy (HIE) [ 10 ], and those parenchymal injuries following hypoglycaemia. Most of these lesions are clinically subtle or silent in the neonatal period, remaining undiagnosed until later in childhood, and may contribute to explain the increased risk of impaired neurobehavioral outcome in LPs compared to term infants reported in the literature [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Cranial ultrasound findings in late preterm infants and correlation with perinatal risk factors

et al. 2015

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BackgroundLate preterm infants are the most represented premature babies. They are exposed to a wide spectrum of brain lesions which are often clinically silent, supporting a possible role of cerebral ultrasound screening. Aim of the study is to describe the pattern of cranial ultrasound abnormalities in late preterm infants and to define the need for cranial ultrasound according to perinatal risk factors.MethodsA hospital-based cranial ultrasound screening was carried out by performing two scans (at 1 and 5 weeks). Unfavorable cranial ultrasound at 5 weeks was defined as either persistent periventricular hyperechogenicity or severe abnormalities.ResultsOne thousand one hundred seventy-two infants were included. Periventricular hyperechogenicity and severe abnormalities were observed in, respectively, 19.6 % and 1 % of late preterms at birth versus 1.8 % and 1.4 % at 5 weeks. Periventricular hyperechogenicity resolved in 91.3 %. At the univariate analysis gestational age (OR 0.5, 95 % CI 0.32-0.77), Apgar score <5 at 5’ (OR 15.3, 1.35-173) and comorbidities (OR 4.62, 2.39-8.98) predicted unfavorable ultrasound at 5 weeks. At the multivariate analysis the accuracy in predicting unfavorable ultrasound, estimated by combined gestational age/Apgar/comorbidities ROC curve, was fair (AUC 74.6) and increased to excellent (AUC 89.4) when ultrasound at birth was included.ConclusionGestational age and comorbitidies are the most important risk factors for detecting brain lesions. The combination of being born at 34 weeks and developing RDS represents the strongest indication to perform a cranial ultrasound. Differently from other studies, twin pregnancy doesn’t represent a risk factor.

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Section: Introductionmentioning

confidence: 99%

Cranial ultrasound findings in late preterm infants and correlation with perinatal risk factors

et al. 2015

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Are We Missing a Vulnerable Population in Early Intervention?

Blasco

Guy

Saxton

et al. 2017

Infants &Amp; Young Children

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Infants with low birth weight (LBW ≤ 2,500 g) are at high risk for developmental delays, including cognitive impairments. Retrospective studies have shown that these children often have learning and/or behavioral difficulties at school age. Early evaluation and enrollment in early intervention (EI) programs may reduce the impact of these difficulties; however, many children who would benefit from such programs may not receive EI services. This study provides information on 279 children born LBW and includes information on developmental capability and EI enrollment. Results indicate that children born LBW in EI services had lower overall developmental standard scores than those not in EI. However, it is concerning that almost an equal number of children across all categories of birth weight are not in services.

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Late preterm and early term children: the early years at school

Cited by 2 publications

References 7 publications

Cranial ultrasound findings in late preterm infants and correlation with perinatal risk factors

Cranial ultrasound findings in late preterm infants and correlation with perinatal risk factors

Are We Missing a Vulnerable Population in Early Intervention?

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