Late Results of Operative Treatment of Cervical Myelopathy

Roosen, K.; Grote, W

doi:10.1007/978-3-642-67605-5_14

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…A number of reports show a better surgical outcome if symptoms have been present less than 1 year. 13,22,25,27,36 The results of this study suggest a pathophysiological mechanism that explains this phenomenon. Neurological improvement seen in the decompressed group supports the theory of CSM pathogenesis previously proposed.…”

Section: Discussionmentioning

confidence: 79%

Experimental chronic compressive cervical myelopathy: effects of decompression

Hl¹,

Al‐Mefty²,

Marawi³

et al. 1995

Journal of Neurosurgery

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Twelve dogs developed a delayed onset of neurological abnormalities from chronic cervical cord compression that was characteristic of myelopathy. The animals were divided into two groups and matched according to degree of neurological deficit. Six animals underwent decompression through removal of the anteriorly placed compressive device. Throughout the experiment, serial neurological examinations and somatosensory evoked potential studies were performed on each animal. Spinal cord blood flow measurements were obtained during each surgical procedure and at sacrifice. Magnetic resonance images were obtained after compression and before sacrifice. All animals in the decompressed group showed significant neurological improvement after decompression; no spontaneous improvement in neurological function was seen in the compressed group. On pathological examination, irreversible changes including large motor neuron loss, necrosis, and cavitation were seen in four of the animals in the decompressed group and five in the compressed group. Cervical spondylotic myelopathy in humans is known to respond to decompression; this study provides further evidence that this animal model for chronic compressive cervical myelopathy accurately reflects the disease process seen in humans.

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Section: Discussionmentioning

confidence: 79%

Experimental chronic compressive cervical myelopathy: effects of decompression

Hl¹,

Al‐Mefty²,

Marawi³

et al. 1995

Journal of Neurosurgery

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“…In a retrospective study of 109 patients with cervical radiculopathy and 55 with cervical myelopathy, Bertalanffy and Eggert 8 found that duration of symptoms beyond 12 months significantly correlated with worse outcomes as assessed by the evaluation criteria set forth by Roosen and Grote. 23 Using the more common European Myelopathy Score, Heidecke and colleagues 9 arrived at the same conclusion from a retrospective review of 106 patients. In a large retrospective review of 248 patients, Pumberger and colleagues 11 found that patients who did not improve following surgical decompression for CSM, where improvement was defined as a reduction of at least 1 Nurick grade, had an average of 17.85 months of preoperative symptoms, whereas those who did improve had symptoms for an average of 11.21 months.…”

Section: Discussionmentioning

confidence: 83%

The Effect of Age on the Benefits of Early Decompression for Cervical Spondylotic Myelopathy

Kusin¹,

Ahn²,

Ahn³

2018

Am J Orthop

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Decompression of cervical myelopathy within 24 months of symptom onset results in greater functional improvement compared to delayed decompression. The improvement with respect to time is more significant for patients older than 65 years compared to younger patients. Duration of symptoms does not seem to influence the severity of the preoperative Nurick score. Preoperative severity of symptoms is related to postoperative outcomes. Other significant predictors of worse outcomes include tobacco use, diabetes, and number of levels fused.

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Der posttraumatische zervikale Bandscheibenvorfall -Radikulo/Medullopathie beim „Soft and Hard Disc“

Klages¹

1999

Hefte Zur Zeitschrift „Der Unfallchirurg“

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Late Results of Operative Treatment of Cervical Myelopathy

Cited by 4 publications

References 22 publications

Experimental chronic compressive cervical myelopathy: effects of decompression

Experimental chronic compressive cervical myelopathy: effects of decompression

The Effect of Age on the Benefits of Early Decompression for Cervical Spondylotic Myelopathy

Der posttraumatische zervikale Bandscheibenvorfall -Radikulo/Medullopathie beim „Soft and Hard Disc“

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