Sets of marine terraces, sediments, and paleoshorelines are commonly found in forearc regions worldwide. A common assumption holds that crustal uplift prevents these features from littoral erosion. Here, we study the vertical deformation of Karpathos, a forearc island in the eastern Mediterranean, whose long axis extends at a high angle to the strike of the Hellenic Subduction System (HSS). We target three key coastal localities along the island to discuss spatial and temporal variability of vertical motion. We mapped sets of up to 19 marine terraces per locality, with elevations ranging from 1.5 to ∼350 masl. Ages for terraces and sediments are constrained by radiocarbon (<31 masl) and Sr‐isotope (2–310 masl) dating, and range from 2.4 ka to ∼4.3 Ma. Data analysis shows that average uplift rates are up to two orders of magnitude faster over shorter (⪅100 ka) than longer (⪆100 ka) timescales, in agreement with other local and global data sets. Further, we find evidence for multiple marine reoccupations of late Pleistocene terraces, indicating that carbonate beachrock is often resistant to multiple interactions with sea‐level. Neogene marine sequences that witness longer periods (∼4 Ma) show signs of alternating vertical motion. Using this novel data set, we explore the effects of various mechanisms (i.e., upper‐plate normal faulting, splay‐thrust faulting, basal underplating) on the spatial and temporal patterns of vertical deformation. Although the contribution of each mechanism to the net vertical deformation cannot be isolated with certainty, our results show that none alone could account for the observations.