2014
DOI: 10.1016/j.oraloncology.2014.09.005
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Late stage diagnosis of oral cancer: Components and possible solutions

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Cited by 153 publications
(147 citation statements)
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References 82 publications
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“…Microscopic evaluation is understood to be required to establish the final diagnosis and, thus, the appropriate treatment in all cases of PMD and malignant lesions. 19,20 In many clinical cases, the lines dividing diagnoses of benign, PMD, and malignant lesions are very thin; clinicians face the challenges of formulating diagnostic hypotheses and predicting which PMD lesions will progress to malignancy. 33 A recent systematic review assessed the diagnostic accuracy of adjunctive tests combined with oral examination for oral cancer; due to the overall poor quality of studies included, the authors failed to identify a replacement for biopsy and histological assessment for final diagnosis.…”
Section: Discussionmentioning
confidence: 99%
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“…Microscopic evaluation is understood to be required to establish the final diagnosis and, thus, the appropriate treatment in all cases of PMD and malignant lesions. 19,20 In many clinical cases, the lines dividing diagnoses of benign, PMD, and malignant lesions are very thin; clinicians face the challenges of formulating diagnostic hypotheses and predicting which PMD lesions will progress to malignancy. 33 A recent systematic review assessed the diagnostic accuracy of adjunctive tests combined with oral examination for oral cancer; due to the overall poor quality of studies included, the authors failed to identify a replacement for biopsy and histological assessment for final diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…However, oral examination alone is not sufficient for the detection and accurate distinction of benign, PMD, and malignant lesions. 19,20 Clinical screening followed by histopathological analysis is crucial, given the estimated annual number of new lip cancer cases worldwide and the wide range of lesions that occur in this location. 21,22 Biopsy, paired with clinical examination, is recommended for final diagnosis; in addition, this approach is recommended when lesions persist despite treatment or the removal of local irritants (of traumatic or inflammatory origin), when lesions do not recede in 2 weeks, when malignancy is suspected, and when lesions interfere with function or impair aesthetics.…”
Section: Introductionmentioning
confidence: 99%
“…Figures 1, 2 and 3 are based on several studies and show factors that may aid in understanding the late diagnosis for oral cancer in Brazil and in other countries. [6][7][8][9][10] The need for continuing education for healthcare professionals is one of these determining factors. Therefore, there is a need to improve public health education programs in order to promote new competences and knowledge that will reduce the impacts and the time spent between self-perception of signs and symptoms all the way until therapy.…”
Section: -4mentioning
confidence: 99%
“…Major factors of delayed diagnosis related to access (based on previous studies). [6][7][8][9][10] Lack of provision of diagnostic services Lack of staff Inadequate time Health system based on hospital-centered model Access not based on the Family Health Program…”
Section: -4mentioning
confidence: 99%
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