2016
DOI: 10.1099/jgv.0.000562
|View full text |Cite
|
Sign up to set email alerts
|

Late stages of the influenza A virus replication cycle—a tight interplay between virus and host

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
20
0
1

Year Published

2017
2017
2024
2024

Publication Types

Select...
3
2

Relationship

0
5

Authors

Journals

citations
Cited by 20 publications
(21 citation statements)
references
References 165 publications
(214 reference statements)
0
20
0
1
Order By: Relevance
“…Upon replication, these viruses must ensure stoichiometric incorporation of single copies of each gRNA segment into new particles. This is guided by specific packaging signals on each segment of gRNA that interact with positively charged domains in the capsid proteins [reviewed in (Isel et al, 2016;Pohl et al, 2016)]. Although different models of packaging have been proposed for various segmented genome viruses, a common feature is co-assembly of the capsid proteins with the gRNA and RNA polymerase.…”
Section: Replication Of Rna Virusesmentioning
confidence: 99%
See 1 more Smart Citation
“…Upon replication, these viruses must ensure stoichiometric incorporation of single copies of each gRNA segment into new particles. This is guided by specific packaging signals on each segment of gRNA that interact with positively charged domains in the capsid proteins [reviewed in (Isel et al, 2016;Pohl et al, 2016)]. Although different models of packaging have been proposed for various segmented genome viruses, a common feature is co-assembly of the capsid proteins with the gRNA and RNA polymerase.…”
Section: Replication Of Rna Virusesmentioning
confidence: 99%
“…The presence of membrane glycoproteins at the Golgi membrane determines the sites where assembling bunyavirus particles bud into the Golgi lumen, similar to other enveloped viruses. Numerous viruses, including paramyxoviruses (Cox and Plemper, 2017), orthomyxoviruses (Pohl et al, 2016), alphaviruses (Jose et al, 2009), rhabdoviruses (Okumura and Harty, 2011), and most retroviruses (Freed, 2015), assemble underneath the cytoplasmic membrane, which facilitates assembly by providing a scaffolding function. The virus then acquires a lipid envelope through budding across the plasma membrane.…”
Section: Assembly In the Cytoplasmmentioning
confidence: 99%
“…The COPI system is essential for correct localisation of IAV particles, while HCV utilises the COPII system to travel from the ER to the Golgi, at which point it can be trafficked through the VLDL secretory pathway (Pohl et al 2016;Syed et al 2017). These systems are regulated in part by Rab GTPases, host cell enzymes which play an important role in trafficking throughout the cell (Hutagalung and Novick 2011) and which have been implicated in the egress of multiple viruses (Hogue et al 2014;Pohl et al 2016;Takacs et al 2017). Rab11 has been shown to be essential for the trafficking of IAV RNA from the perinuclear region to the plasma membrane (Pohl et al 2016).…”
Section: Viral Assembly and Egressmentioning
confidence: 99%
“…These systems are regulated in part by Rab GTPases, host cell enzymes which play an important role in trafficking throughout the cell (Hutagalung and Novick 2011) and which have been implicated in the egress of multiple viruses (Hogue et al 2014;Pohl et al 2016;Takacs et al 2017). Rab11 has been shown to be essential for the trafficking of IAV RNA from the perinuclear region to the plasma membrane (Pohl et al 2016). Another Rab protein, Rab1, has been proposed to mediate transport of nascent HCV virions from the ER to the Golgi (Takacs et al 2017).…”
Section: Viral Assembly and Egressmentioning
confidence: 99%
See 1 more Smart Citation