Latent myasthenia gravis revealed by protracted postoperative effect of non-depolarizing neuromuscular blockade

Ito, Shoji; Fujita, Yoshihito; Sasano, Hiroshi; Sobue, Kazuya

doi:10.1007/s00540-012-1432-4

Cited by 6 publications

(3 citation statements)

References 2 publications

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“…Полная ремиссия описывается в 10-20% случаев через 5 лет по сравнению с 30-60% при миастении без тимомы. Таким образом, тимома является плохим прогностическим фактором из-за меньшего ответа на лечение и большей тяжести симптомов у пациентов [31][32][33][34][35].…”

Section: консультация торакального хирурга оперативное вмешательство ...unclassified

Анализ Заболеваемости Верифицированных Случаев Миастении В Центральном Казахстане

Григолашвили,

Евстафьева,

Муратбекова

et al. 2023

АЖЗС

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Section: консультация торакального хирурга оперативное вмешательство ...unclassified

Анализ Заболеваемости Верифицированных Случаев Миастении В Центральном Казахстане

Григолашвили,

Евстафьева,

Муратбекова

et al. 2023

АЖЗС

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“…Полная ремиссия описывается в 10-20 % случаев через 5 лет по сравнению с 30-60 % при нетимоматозной формой миастении. Таким образом, тимома является плохим прогностическим фактором из-за меньшего ответа на лечение и большей тяжести симптомов у пациентов [31,32,33,34,35].…”

Section: проведение кт средостения (выявленное наличие тимомы гиперпл...unclassified

Morbidity analysis of verified cases of myasthenia gravis in central Kazakhstan

Grigolashvili,

Evstafyeva,

Beisembayeva

et al. 2023

jour

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Introduction.Myasthenia gravis is a chronic autoimmune disease that manifests itself as a syndrome of pathological muscle fatigue. Epidemiological studies show a change in the course of the disease due to the COVID-19 pandemic.The purpose of the study. Analysis of features of cohort of patients with myasthenia gravis in Central Kazakhstan.Materials and methods. A retrospective analysis of case histories of 98 patients with myasthenia gravis treated from January 2020 to December 2022 in the neurological departments of Karaganda region (Central Kazakhstan) was carried out.Results. The ratio of men and women was 1:2.2. 46% of patients had onset of the disease aged 18 to 39 years. In the debut of disease, the ocular and generalized forms are presented in an equal ratio. Comorbidity prevails in the elderly. CT-signs of thymoma were detected in 23% of patients. All the studied patients received therapy with pyridostigmine bromide, glucocorticoids; cytostatic therapy – 1 patient; immunoglobulin G – 1 patient; there were no patients with therapy with monoclonal antibodies.Conclusions. There are gender and age characteristics, differences in the course of the disease and comorbidity in patients with myasthenia gravis in Central Kazakhstan, in comparison with other countries. Improvements are needed in the field of immunological diagnostics and, according to indications, the introduction of international treatment regimens.

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“…If the use of pyridostigmine is stopped, a smaller dose of the non-depolarizing neuromuscular relaxant will be used 20,21 .…”

Section: Balanced General Anesthesiamentioning

confidence: 99%

Perioperative management of the patient with Myasthenia gravis

Ortíz-Benítez

Carrillo‐Torres

Mendoza-Escoto

et al. 2019

HGMX

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Myasthenia gravis is an autoimmune disease in which autoantibodies interact postsynaptic nicotinic acetylcholine at the neuromuscular junction which decreases the capacity of the terminal plate to transmit the nerve signal. For the anesthesiologist may be difficult extubation at the end of the procedure, especially if interference drugs are used at the neuromuscular junction. This review addresses the steps to be followed in perioperative management with flowcharts.

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Latent myasthenia gravis revealed by protracted postoperative effect of non-depolarizing neuromuscular blockade

Cited by 6 publications

References 2 publications

Анализ Заболеваемости Верифицированных Случаев Миастении В Центральном Казахстане

Анализ Заболеваемости Верифицированных Случаев Миастении В Центральном Казахстане

Morbidity analysis of verified cases of myasthenia gravis in central Kazakhstan

Perioperative management of the patient with Myasthenia gravis

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