Lateral migration of dual droplet trains in a double spiral microchannel

Xue, Changfeng; Chen, Xiao; Liu, Chao; Hu, Guoqing

doi:10.1007/s11433-016-0115-1

Cited by 7 publications

(7 citation statements)

References 53 publications

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“…The two identical side openings are for continuous phases, which are then merged into one main inlet for easy control in actual operation. The chip was fabricated in polydimethylsiloxane (PDMS), based on the standard soft-lithography technique as described previously [48,49]. Before the experiments, the chips were kept in an oven at 80 • C overnight to restore the material to its native hydrophobic condition.…”

Section: Methodsmentioning

confidence: 99%

Breakup Dynamics of Semi-dilute Polymer Solutions in a Microfluidic Flow-focusing Device

Xue

Chen

et al. 2020

Micromachines

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Droplet microfluidics involving non-Newtonian fluids is of great importance in both fundamental mechanisms and practical applications. In the present study, breakup dynamics in droplet generation of semi-dilute polymer solutions in a microfluidic flow-focusing device were experimentally investigated. We found that the filament thinning experiences a transition from a flow-driven to a capillary-driven regime, analogous to that of purely elastic fluids, while the highly elevated viscosity and complex network structures in the semi-dilute polymer solutions induce the breakup stages with a smaller power-law exponent and extensional relaxation time. It is elucidated that the elevated viscosity of the semi-dilute solution decelerates filament thinning in the flow-driven regime and the incomplete stretch of polymer molecules results in the smaller extensional relaxation time in the capillary-driven regime. These results extend the understanding of breakup dynamics in droplet generation of non-Newtonian fluids and provide guidance for microfluidic synthesis applications involving dense polymeric fluids.

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Section: Methodsmentioning

confidence: 99%

Breakup Dynamics of Semi-dilute Polymer Solutions in a Microfluidic Flow-focusing Device

Xue

Chen

et al. 2020

Micromachines

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“…18,19 Most of the effort in this field is focused on the control of solid particles with diameters smaller than the size of the channel; typically, by one order of magnitude. [20][21][22][23][24][25][26][27][28][29][30] Although there are similarities between the behavior of rigid particles and bubbles, deformation of the bubbles [31][32][33][34] complicates the understanding of the physical phenomena evidenced in gas/liquid flows. Understanding the active forces affecting bubble motion is necessary in order to explain its behavior.…”

Section: Introductionmentioning

confidence: 99%

Inertial manipulation of bubbles in rectangular microfluidic channels

et al. 2018

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Inertial microfluidics is an active field of research that deals with crossflow positioning of the suspended entities in microflows. Until now, the majority of the studies have focused on the behavior of rigid particles in order to provide guidelines for microfluidic applications such as sorting and filtering. Deformable entities such as bubbles and droplets are considered in fewer studies despite their importance in multiphase microflows. In this paper, we show that the trajectory of bubbles flowing in rectangular and square microchannels can be controlled by tuning the balance of forces acting on them. A T-junction geometry is employed to introduce bubbles into a microchannel and analyze their lateral equilibrium position in a range of Reynolds (1 < Re < 40) and capillary numbers (0.1 < Ca < 1). We find that the Reynolds number (Re), the capillary number (Ca), the diameter of the bubble (D[combining macron]), and the aspect ratio of the channel are the influential parameters in this phenomenon. For instance, at high Re, the flow pushes the bubble towards the wall while large Ca or D[combining macron] moves the bubble towards the center. Moreover, in the shallow channels, having aspect ratios higher than one, the bubble moves towards the narrower sidewalls. One important outcome of this study is that the equilibrium position of bubbles in rectangular channels is different from that of solid particles. The experimental observations are in good agreement with the performed numerical simulations and provide insights into the dynamics of bubbles in laminar flows which can be utilized in the design of flow based multiphase flow reactors.

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“…A key parameter for the identification of particles and perhaps a cell cycle indicator was the form and architecture of the double spiral microchannel 75,[249][250][251][252][253][254] . A double spiral microchannel was investigated by Xue et al (2016) for the adjacent motion of two-fold droplets train at small Reynolds number. Droplet motion was employed to addition and transference the tiny particles in these channels, supply the lowest scale, release segments for the analysis, catch cells for exposure, and deliver [255][256][257][258][259] .…”

Section: Double Spiral Microchannelmentioning

confidence: 99%

“…Droplet motion was employed to addition and transference the tiny particles in these channels, supply the lowest scale, release segments for the analysis, catch cells for exposure, and deliver [255][256][257][258][259] . They talked about the effectiveness of migration and the impact of droplet deformation on motion in these channels 165) .…”

Section: Double Spiral Microchannelmentioning

confidence: 99%

A Review on Microchannel Fabrication Methods and Applications in Large-Scale and Prospective Industries

Afzal¹,

Tayyaba²,

Ashraf³

et al. 2022

Evergreen

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Microchannels based on microelectromechanical systems (MEMS) have received a lot of interest in the microfluidics and biomedical fields over the past forty years. While their applications have been multifarious, a comprehensive literature review focusing on their design, type, and applications is not currently present in the literature. Researchers working on these elements of microchannels will gain targeted knowledge from the current review on microchannels. Due to its advanced properties, flexibility of mass, and small size, microdevice demand has been rising quickly, particularly in industrial applications. The classification of microchannels and their uses are the main focus of this work. These include but are not limited to molding, electroplating, lithography, lab-ona-chip, micromolding, micromachining, micromilling, laser ablation, lithography, microcontact printing (µcp), hot embossing, electrochemical micromachining (EMM), and etching. In addition, numerous hybrid techniques for microchannel manufacturing have been reported. So, in essence, this review offers a range of advancements in microchannel manufacturing. The review also attempts to present a qualitative analysis describing the various methodologies associated with microchannels in terms of their design, shape, and flow regimes for applications such as pressure drop and transfer of heat prediction. Additionally, depending on the precise uses needed, a number of materials, including but not limited to ceramics, silicon, metals, and polymers, are utilized in the manufacture of microchannels. On metallic substrates, polymers such as silicon, glass, and polymeric materials are used. The biomedical industry uses polymeric and glass substrates instead of silicon substrates, which are used for mechanical engineering and electronic applications. In addition to outlining methods for choosing the best kind of microchannel, this paper also suggests important directions for the future.

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Lateral migration of dual droplet trains in a double spiral microchannel

Cited by 7 publications

References 53 publications

Breakup Dynamics of Semi-dilute Polymer Solutions in a Microfluidic Flow-focusing Device

Breakup Dynamics of Semi-dilute Polymer Solutions in a Microfluidic Flow-focusing Device

Inertial manipulation of bubbles in rectangular microfluidic channels

A Review on Microchannel Fabrication Methods and Applications in Large-Scale and Prospective Industries

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