Lateral migration of spherical particles in porous flow channels: application to membrane filtration

Colloidal fouling of microfiltration membranes during the treatment of aqueous feed streams

“…It is known that the fouling layer which appears during crossflow microfiltration is invariably formed from the finer particle species present in the feed suspension 8,9 . The axial velocity gradient which is generated across the flow channel causes the larger particles in suspension to migrate away from the septum at a faster rate than the smaller ones 10 , hence the layer responsible for membrane fouling could have a resistance considerably higher than that which might be expected from a simplistic approach.…”

Optimizing the operation of a direct-flow filtration device

“…In general, at a permeable wall there is a tangential slip velocity, whose magnitude is determined by a Neumann boundary condition such as that given in [23]. However, it has been found that this slip is not significant for a wide range of membranes [24,25] and so here, for simplicity, we shall assume a no-slip boundary condition. Mathematically the boundary conditions may be expressed as Symmetry:…”

Recovery and purification process development for monoclonal antibody production

“…Membrane fouling is limited by the inertial lift and shear-induced diffusion generated by the laminar flow across the membrane surface. [7][8][9][10] A high yielding harvest is achieved by a series of concentration and diafiltration steps. In the former, the volume of the CCF is reduced, thereby concentrating the solid mass.…”