Lateral Supratentorial Endodermal Cyst: Case Report and Review of Literature

Abstract

This case involved the occurrence of a solitary endodermal cyst as an extra-axial mass localized over the lateral frontal lobe. The lateral supratentorial localization of this lesion illustrates the need for consideration of the pathogenesis of this entity as well as its diagnostic differentiation from other cystic abnormalities in this region. A review of the histochemistry of endodermal, neuroepithelial, and other cerebral cysts is presented.

Intraparenchymal Supratentorial Neurenteric Cyst

“…Furthermore, cyst leakage has been known to cause meningeal irritation and infection. 11 The case presented in this report and the cases presented by Bavetta et al 12 and Cheng et al 13 have all involved intracranial cysts that were diagnosed only when they reached a very large size (4-5 cm). This is probably due to their frontal location.…”

“…3,11,13,[15][16][17][18] Intracranial neurenteric cysts are more frequent in the posterior fossa in comparison to the supratentorial area. Cyst locations in the posterior fossa include the fourth ventricle, the prepontine space, adjacent to the jugular foramen, the cerebellopontine angle, the cerebellar vermis and within the medulla.…”

“…2,8,[20][21][22][23] Ten cases of supratentorial neurenteric cysts have been previously reported. Cyst locations include the parasellar/suprasellar region, 14,17 the septum pellucidum, 16 the third ventricle, 3 the orbital apex/superior orbital fissure, 15 the optic nerve, 18 and the extraaxial anterior cranial fossa 12,13,19 (Table). None of these cysts was contained within the brain parenchyma.…”

“…1 7 Neurenteric cysts stain positive for cytokeratin markers, and are negative for neuronal and ectodermal markers such as GFAP, S-100, neuron specific enolase and synaptophysin. 3,13,14 Neurenteric cysts are usually, but not always, positive for CEA which is a marker of the embryonic gastrointestinal tract. 2 , 1 4 Ependymal cysts react positively for GFAP and negative for cytokeratin and CEA.…”

“…1 0 , 11 S u p r a t e n t o r i a l neurenteric cysts are very rare and none of the cysts in those cases reported to date have been located within the brain parenchyma. 3,[12][13][14][15][16][17][18][19] We report a case of a 35-year-old female who underwent successful excision of an intraaxial right frontal lobe neurenteric cyst. To our knowledge, this is the first case report of A B S T R A C T: B a c k g r o u n d : Neurenteric cysts are congenital cysts of the central nervous system that are believed to be of endodermal origin.…”