Laterality of cervical disc herniation

Abstract

Purpose Cervical disc herniation (CDH) is found more frequently at the lower cervical spine than at the upper or middle level. However, there is scarcity of data about the laterality of CDH. The aim of this study is to detect the laterality of CDH. Methods We retrospectively evaluated preoperative computed tomography myelograms and magnetic resonance images of 75 cases of CDH who underwent single level anterior cervical discectomy and fusion at C4-5, C5-6, or C6-7 levels from 2008 to 2010 in our institute. Statistical analyses were performed using the Chi-square test. Results Eleven cases were found at C4-5 level, 42 cases at C5-6 level, and 22 cases at C6-7 level. At C4-5 level, CDH was recognized at the right side in 2 cases, at the left side in 2 cases, and at the center in 7 cases. At C5-6 level, CDH was found at the right side in 20 cases and at the left side in 22 cases. At C6-7 level, CDH was found at the right side in 3 cases and at the left side in 19 cases with significantly high frequency of left-sided CDH (p \ 0.025). Conclusions In this study, it was revealed that the leftsided CDH was more frequent than the right-sided CDH at C6-7 level.

Altered expression of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in cervical disc herniation patients

“…In general, CDH can lead to neck and upper extremity pain, myelopathy, or radiculopathy resulting in numbness, weakness, or paresthesias (McCormick et al, 2003;Abbed and Coumans, 2007). Although the exact pathogenesis of CDH remains unclear, it is widely accepted that mechanical stress may be an important factor in the development of CDH and facet joint degeneration (Takahashi et al, 2013). It is well understood that the IVD performs key mechanical functions in distributing spinal load and maintaining flexibility (Loreto et al, 2011).…”

A New Automated AI-Assisted System to Assess Cervical Disc Herniation

“…Degenerative cervical myelopathy, as the very common form of spinal cord impairment,1,2 gains in popularity with the aging of population world-wide 3. Due to disc degeneration, the fragment of disc (mainly nucleus pulposus) is pushed into the spinal canal via a rupture in the annulus, referred to cervical disc herniation (CDH),4 compressing the spinal cord/spinal nerve roots thus leading to clinical manifestations. Revealed by magnetic resonance imaging (MRI), CDH was the only finding significantly associated with clinical symptoms 5.…”