Despite Census Bureau projections that youth from minority cultures will comprise the majority of the nation's youth in approximately a decade, little research has been conducted on culturally sensitive interventions (CSIs). Accordingly, this study sought to determine: (1) the effectiveness of CSIs designed to address health and behavioral health outcomes, (2) whether effectiveness varies depending on the class or type of outcome, and (3) whether race/ethnicity moderates effectiveness. The results suggest that CSIs (n = 21) are modestly effective (Hedges' g = .239, 95% C.I. = .139 to .339, p < .001). Effectiveness did not vary significantly by outcome class or by race/ethnicity. Especially in the latter case, however, the pattern of point estimates raises the possibility of moderation with an increase in power. Suggestions for future research conclude the article.