Musculoskeletal tissues are a complex system which provides form, support, stability, and movement to the body. It is also characterized by natural mechano-responsiveness and an efficient complementarity among muscles, tendons, ligaments, cartilage, and bones necessary for function and coordinated actions both for daily life and the most demanding sports activities. The musculoskeletal system relies on the proper articulation of soft and hard tissues tailored to accomplish specific functions (Fig. 3.1).