Abstract. In the present study, a combination of Lattice Boltzmann Method (LBM) and Smoothed Pro le Method (SPM) is used to simulate one, two, and many particles motion in a planar channel with two symmetric protuberances. LBM is applied as the uid ow solver and SPM is used to satisfy the no-slip boundary condition at particles surfaces. Bounceback boundary conditions are used for lower and upper walls while pressure boundary conditions are applied for the uid inlet and outlet boundaries. Horizontal, vertical, and angular velocities of particles are recorded during the simulation. It is concluded that the combined LBM-SPM can be considered as a good candidate for simulation of particle motion in a channel with stenotic geometry.