Layer-by-layer assembled gold nanoparticle films on amine-terminated substrates

Zhang, Fengxiang; Srinivasan, M.P.

doi:10.1016/j.jcis.2007.12.008

Cited by 37 publications

(27 citation statements)

References 43 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have got similar Goulet et al [19] and Zhang and Srinivasan [21] results when an LbL film containing PAH/(DPPG+MB) was left 30 min soaked into Ag colloid. For instance, Figure 3(a) shows the UV-Vis absorption spectra for a 21-bilayer PAH/(DPPG+MB) LbL film, which was left soaked for a total of 5 h into the Ag colloid (ten steps of 30 min) with the spectra being collected every 30 min.…”

Section: Resultssupporting

confidence: 85%

“…[19] In terms of Ag colloid aggregation, the tail in the UV-Vis spectrum without a characteristic broad absorption band indicates low level of aggregation. [19,21] Besides, the changes observed in the UV-Vis spectra of the Ag colloid containing DPPG and DPGG+MB suggest that the aggregation of the Ag particles in the colloid is not significantly affected. In the case of the Ag colloid containing MB, particularly, its UV-Vis spectrum is a simple superposition of the UV-Vis spectra of the Ag colloid and the MB.…”

Section: Resultsmentioning

confidence: 99%

“…[31] It is important to mention as well that the AgNP aggregation level does not seem to be considerably affected as these LbL films are grown. For instance, Goulet et al [19] working with LbL films containing bilayers of dendrimers/AgNP and Zhang and Srinivasan [21] working with LbL films containing bilayers of PAH/AuNP [21] reported a strong increase of the UV-Vis absorption band with maximum at ca 650 nm assigned to the noble metal particle aggregates. The main reason for this difference might be the time that the LbL film is left soaked into Ag or Au colloids, which was found to be 2 h in Goulet et al, [19] 30 min in Zhang and Srinivasan, [21] and 3 min in our case.…”

Section: Resultsmentioning

confidence: 99%

“…Alternatively, SERS active substrates have been made by the simple and powerful self-assembled layer-by-layer (LbL) technique, [18 -20] which is a distinct approach to prepare well-defined and controlled nanostructures. The LbL technique becomes advantageous because it allows the immobilization of nanoparticles, in the form of alternated layers, with a range of different materials such as dendrimers, [19] polymers, [21,22] polysaccharides, [23] , and DNA. [24] Moreover, one can take the advantage of this technique to investigate possible interactions between the materials constituting the film with a specific analyte using SERS as an analytical tool.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Incorporation of Ag nanoparticles into membrane mimetic systems composed by phospholipid layer‐by‐layer (LbL) films to achieve surface‐enhanced Raman scattering as a tool in drug interaction studies

Aoki

Aléssio

Saja

et al. 2009

J Raman Spectroscopy

View full text Add to dashboard Cite

The synergistic effect produced by nanoparticles when incorporated into different systems used as analytical tools represents a growing research field nowadays. On the other hand, the study of interactions involving pharmacological drugs and biological membranes using phospholipids as mimetic systems is a research field already well established. Here, we combine both the anionic phospholipid dipalmitoyl phosphatidyl glycerol (DPPG) and negative Ag nanoparticles (AgNP) to form layer-by-layer (LbL) multilayered films using the cationic polymer poly(allylamine hydrochloride) (PAH) as the supporting polyelectrolyte, which were further investigated in the presence of a phenothiazine compound (methylene blue -MB). The molecular architecture of the LbL films in terms of controlled growth, morphology with micro and nanometer spatial resolutions, and dispersion of both AgNP and MB within the DPPG matrix was determined combining spectroscopy [ultraviolet-visible (UV-Vis) absorption and micro-Raman spectroscopy] and microscopy [scanning electron microscopy (SEM) and atomic force microscopy (AFM)].The results showed that the LbL films can be grown in a controlled way at nanometer thickness scale with the surface morphology susceptible to the presence of both AgNP and MB. The surface-enhanced phenomenon was applied to investigate the LbL films taking the advantage of the strong surface-enhanced resonance Raman scattering (SERRS) signal presented by the MB molecules. Besides, as MB is a pharmacological drug of interest, its molecular arrangements when dispersed in LbL films containing DPPG, which is the biological membrane mimetic system here, were investigated. In this case, the AgNP played a key role in achieving the MB SERRS signal.

show abstract

Section: Resultssupporting

confidence: 85%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incorporation of Ag nanoparticles into membrane mimetic systems composed by phospholipid layer‐by‐layer (LbL) films to achieve surface‐enhanced Raman scattering as a tool in drug interaction studies

Aoki

Aléssio

Saja

et al. 2009

J Raman Spectroscopy

View full text Add to dashboard Cite

show abstract

“…After the pioneering works on the preparation of Au thin films [1,2], numerous other methods were developed involving techniques such as electrostatic controlled assembly [40], layer-bylayer assembly [16,41,42], interfacial entrapment [43], micromolding lithography [44], and centrifugal force-aided deposition [45]. In this study, the mixtures consisting of hybridized Au NPs and isolated copolymer micelles were spin-coated onto solid substrates to fabricate composite Au thin films.…”

Section: Fabricating Au Thin Films By Spin-coatingmentioning

confidence: 99%