Layer-by-Layer Self-Assembled Chitosan/Poly(thiophene-3-acetic acid) and Organophosphorus Hydrolase Multilayers

Constantine, Celeste A.; Mello, Sarita V.; Dupont, Annie; Cao, Xin; Santos, Dos; Oliveira, Osvaldo N.; Strixino, Francisco T.; Pereira, Ernesto C.; Cheng, Thomas K.; DeFrank, Joseph; Leblanc, Roger M.

doi:10.1021/ja028691h

Cited by 145 publications

(93 citation statements)

References 41 publications

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“…2 The fundamentals and potential applications are well described in outstanding recent reviews. 3,4 While in earlier publications the alternated deposition involved polycations and polyanions, over the last years it evolved to the combination of polymers (charged or not) and proteins [3][4][5][6][7][8] or inorganic particles. [9][10][11] The driving force for the stable layer association is entropic in nature and results from the release of counter-ions and water.…”

Section: Introductionmentioning

confidence: 99%

Structural aspects of polyanion and hydrophobically modified polycation multilayers on hydrophilic or hydrophobic surfaces

et al. 2012

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Multilayer films of carboxymethylcellulose (CMC), a polyanion, and bromide salts of poly(4-vinylpyridine) quaternized with linear aliphatic chains of 2 (ethyl) and 5 (pentyl) carbon atoms, coded as QPVP-C2 and QPVP-C5, respectively, were fabricated by layer-by-layer (LbL) self-assembly onto Si/SiO 2 wafers (hydrophilic substrate) or polystyrene, PS, films (hydrophobic substrate). The films were characterized by means of ex situ and in situ ellipsometry, atomic force microscopy (AFM), contact angle measurements and sum frequency generation vibrational spectroscopy (SFG). Antimicrobial tests were used to assess the exposure of pyridinium moieties to the aqueous medium. In situ ellipsometry indicated that for Si/SiO 2 the chains were more expanded than the PS films and both substrates systems composed of QPVP-C5 were thicker than those with QPVP-C2. For dried layers, the alkyl side group size had a small effect on the thickness evolution, regardless of the substrate. At pH 2 the multilayers showed high resistance, evidencing that the build-up is driven not only by cooperative polymer-polymer ion pairing, but also by hydrophobic interactions between the alkyl side chains. The LbL films became irregular as the number of depositions increased. After the last deposition, the wettability of QPVP-C2 or QPVP-C5 terminated systems on the Si/SiO 2 wafers and PS films were similar, except for QPVP-C2 on Si/SiO 2 wafers. Unlike the morphology observed for LbL films on Si/ SiO 2 wafers, PS induced the formation of porous structures. SFG showed that in air the molecular orientation of pyridinium groups in multilayers with QPVP-C5 was stronger than in those containing QPVP-C2. The exposure of pyridinium moieties to the aqueous medium was more pronounced when the LbL were assembled on Si/SiO 2 wafers.

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Section: Introductionmentioning

confidence: 99%

Structural aspects of polyanion and hydrophobically modified polycation multilayers on hydrophilic or hydrophobic surfaces

et al. 2012

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“…Estos estudios han analizado la interacción de los polímeros durante la formación de las películas, así como el efecto de la distribución e interacciones de los compuestos sobre las propiedades físicas, antimicrobianas, químicas, entre otras [59][60][61][62][63][64][65][66][67][68][69][70][71][72][73][74]. Muchas aplicaciones han sido desarrolladas en campos de la investigación como en el área de electrónica [75][76][77][78][79][80][81][82][83][84][85], la inmovilización de enzimas [86][87][88][89], el desarrollo de nuevos materiales con propiedades ópticas específicas [81,[90][91][92], la liberación de compuestos [93][94][95], entre otras.…”

Section: Conformación De Películas En Multicapasunclassified

Modificaciones físicas, químicas y enzimáticas y sus efectos sobre las propiedades de las películas de quitosano

Valderrama

Albarracín

2014

Matéria (Rio J.)

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Modificaciones físicas, químicas y enzimáticas y sus efectos sobre las propiedades de las películas de quitosano.Physical, chemical and enzymatic modifications and their effects on the properties of chitosan films. RESUMENLas recientes investigaciones en el campo de biopolímeros han intentado brindar soluciones tecnológicas a los retos en el campo de la ciencia y la tecnología de los materiales. En los últimos años, se han llevado a cabo investigaciones con el objetivo de modificar las propiedades de películas empleando tratamientos enzimáticos y físicos, tales como la aplicación de radiaciones, pulsos eléctricos, plasma, tratamientos térmicos, uso de fluidos supercríticos, así como la conformación de películas en multicapas. Estas modificaciones cambian las propiedades antimicrobianas, físicas y químicas de las películas de quitosano y permiten desarrollar una extensa cantidad de aplicaciones en los campos de biomedicina, farmacología, biotecnología y en la industria de cosméticos y de alimentos. El objetivo del presente artículo de revisión es dar a conocer los nuevos avances en el campo de modificaciones físicas y enzimáticas de películas de quitosano explicando diferentes técnicas empleadas en los últimos años.Palabras clave: quitosano, polímeros, películas modificadas, aditivos alimenticios. ABSTRACTRecent research on biopolymer has focused its efforts to provide technological solutions to current and future challenges in the field of science and technology of materials. The properties of chitosan films have been modified by enzymatic and physical treatments such as the application of radiation, electric pulses, plasma, heat treatments, use of supercritical fluids as well as the formation of multilayer films. These modifications change antimicrobial, physical and chemical properties of chitosan films, and allow developing a wide range of applications in the fields of biomedicine, pharmacology, biotechnology, cosmetic and food industries. The purpose of this review is to present new developments in the field of physical and enzymatic modifications of chitosan films describing the different techniques carried out on the last years.

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“…Preparation of biosensor by using self-assembly method has been an active research topic in sensor design [55] . With the modified electrode by self-assembly method, some biosensors were prepared to determining paraoxon [56] , sterigmatocystin [57] .…”

Section: ) Immobilizing Enzymes By Crosslinkingmentioning

confidence: 99%

Application and Preparation of Chitosan Electrochemical Sensor

Tan¹

2015

Proceedings of the 2015 International Power, Electronics and Materials Engineering Conference

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Abstract. During the last decade, the sensors based on chitosan had been an active research topic due to its great practical value. The sensors had showed excellent superiority, low cost, ease of fabrication, fast response time and nice repeatability. This review discusses the preparation and application of sensors based on in metallic ion detection, non-metallic ions detection, organic detection and biosensors are reviewed, and future applications are prospected.

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Layer-by-Layer Self-Assembled Chitosan/Poly(thiophene-3-acetic acid) and Organophosphorus Hydrolase Multilayers

Cited by 145 publications

References 41 publications

Structural aspects of polyanion and hydrophobically modified polycation multilayers on hydrophilic or hydrophobic surfaces

Structural aspects of polyanion and hydrophobically modified polycation multilayers on hydrophilic or hydrophobic surfaces

Modificaciones físicas, químicas y enzimáticas y sus efectos sobre las propiedades de las películas de quitosano

Application and Preparation of Chitosan Electrochemical Sensor

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