LC/ESI/MS/MS method development and validation for the determination of sulfonamide antibiotic residues in shrimp sample

REDDY, B. SIDDA; Yadlapalli, Sudhakar; Rao, Yifei; Prasad, P. Reddy; Prabhakar, K.; Sreedhar, N. Y.

doi:10.22147/juc/140105

Cited by 1 publication

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A sensitive and selective method was developed and validated was positive ion LC-MS method of 10 sulfonamides antibiotic residue in raw shrimp meat as per EU guidelines council Directive 2002/657/EC. Method validation parameters are system suitability % RSD range from 10.90 to 18.58%, specificity average area of blank sample was in range from 24 to 273, LOD was in range from 7.2 to 17.7, LOQ was in range from 21.7 to 53.5, recovery at 50ppb level in range between 87.39 and 101.87%, at 100ppb level range between 87.14 and 101.69%, at 150ppb level range between 97.41 and 106.35% with three batches, DL (CCα) were range from 104.72 to 106.60%, DC (CCβ) ranged between 114.33 and 117.98, and for ruggedness % RSD range between 3.11 and 5.19% [ 8 ]. Wang et al .…”

Section: Lc-msmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of various veterinary drug residues in animal originated food products

Parmar

Chaubey

Gupta³

et al. 2021

Vet World

View full text Add to dashboard Cite

The veterinary drugs are broad-spectrum antibacterial antibiotics; it uses to cure the animal disease. Many countries have banned veterinary drug residues like nitrofurans metabolites, chloramphenicol. However, the people were administrated veterinary drugs to animals as illegal to increase the milk production in animals for economic benefit. The results of illegally use of veterinary drugs remain as a residue in animal product like milk and it is very harmful to whom consume it cause cancer and allergic for human being which has entered the concern among milk consumers. To control illegal use of veterinary drugs, the government of India has restricted its use in animals. For the identification and confirmation of veterinary drug residues in animal products, analytical techniques such as liquid chromatography and mass spectrometry are available. These are very sophisticated equipments which are available nowadays and their methodologies for the analytical method validation are described by European commission 2002/657/EC. The use of veterinary drugs is a big challenge to effectively identify and authorization of their use. There are so many analytical techniques are using very effectively and taking very less time to protect the consumers from their adverse effects. These techniques take very less time to identify more groups of compounds such as tetracycline, sulfonamides, anthelmintic, and macrolides in single multi-residue method. These methods having validation parameters include system precision, calibration curve, accuracy, limit of detection, and quantification. Therefore, improvement in the existing technologies and accessibility of new screening methodologies will give opportunities for automation that helps in obtaining the results in very less time and improved sensitivity and specificity which contribute to better safety assurance, standard, and quality of various food products of animal origin.

show abstract

Section: Lc-msmentioning

confidence: 99%

“…The analysis of veterinary drug residues with a different group of antibiotic residues in a single multi-residue method is possible through LC-MS/MS. There are major advantages of LC-MS/MS its gives quantitative as well as confirmative analysis at very low levels [ 8 ].…”

Section: Introductionmentioning

confidence: 99%