LC–ESI-Q-TOF-MS for faster and accurate determination of microcystins and nodularins in serum

Neffling, Milla Riina; Spoof, Lisa; Quilliam, Michael A.; Meriluoto, Jussi

doi:10.1016/j.jchromb.2010.07.018

Cited by 10 publications

(2 citation statements)

References 40 publications

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“…42,43 Nevertheless, despite the high instrumentation cost, analytical techniques are once again the most commonly used method for the determination of cyanobacterial toxins. 65…”

Section: Conventional Detection Methods For Freshwater Toxinsmentioning

confidence: 99%

Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

Campàs

Garibo

Prieto‐Simón

2012

Analyst

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This article gives an overview of the biosensors for the analysis of mycotoxins, marine toxins and cyanobacterial toxins, describing in depth the electrochemical biosensors that incorporate nanobiotechnological concepts. Firstly, it presents tailor-designed biomolecules, such as recombinant enzymes, recombinant antibody fragments and aptamers as novel biorecognition elements in biosensors. It also reviews the use of metallic nanoparticles (NPs) and carbon nanotubes (CNTs) aiming at improving the electrochemical transduction strategies. Finally, the exploitation of magnetic particles (MPs) as immobilisation carriers in flow-systems and the development of arrays are also described. The incorporation of these nanobiotechnological concepts provides with electrochemical biosensors with superior analytical performance in terms of specificity, sensitivity, stability and analysis time.

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“…42,43 Nevertheless, despite the high instrumentation cost, analytical techniques are once again the most commonly used method for the determination of cyanobacterial toxins. 65…”

Section: Conventional Detection Methods For Freshwater Toxinsmentioning

confidence: 99%

Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

Campàs

Garibo

Prieto‐Simón

2012

Analyst

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show abstract

“…most widely used as extraction solvent in biological fluid samples [2,[28][29][30]. In the plasma preparation, methanol was chosen for further development as it had better recoveries (93.7%, 91.1% and 85.8% for MC-RR, MC-RR-GSH and MC-RR-Cys, respectively), which were obviously higher than those of acetonitrile (78.6%, 75.0% and 78.2%) and EDTA-Na 2 (0.01 M)-5% acetic acid (35.6%, 32.9% and 32.8%).…”

Section: Fig 3 Mean Recoveries Of Mc-rr Mc-rr-gsh and Mc-rr-cys Spmentioning

confidence: 99%

Quantitative liquid chromatography–tandem mass spectrometry method for determination of microcystin-RR and its glutathione and cysteine conjugates in fish plasma and bile

Xie

et al. 2014

Journal of Chromatography B

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Specific Methods for the Destruction of Hazardous Chemicals in the Laboratory

Lunn¹,

Sansone²

2012

Destruction of Hazardous Chemicals in the Laboratory

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LC–ESI-Q-TOF-MS for faster and accurate determination of microcystins and nodularins in serum

Cited by 10 publications

References 40 publications

Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxins

Quantitative liquid chromatography–tandem mass spectrometry method for determination of microcystin-RR and its glutathione and cysteine conjugates in fish plasma and bile

Specific Methods for the Destruction of Hazardous Chemicals in the Laboratory

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