The Physical Layer Security mechanism has emerged as a powerful concept that can provide high-level security and can even replace encryption oriented schemes, which necessitate various difficulties and practical challenges for future communication systems (e.g., IoT). Therefore, the critical goal of this work is to enhance the security performance at IoT and prevent the network from various eavesdropping attacks. In this Manuscript, analyze the hardware-based Physical Layer Security solutions and suitable cryptographic Algorithms for IoT applications. The Cryptographical Algorithms include AES, DES, Light Encryption Devices (LED), PRESENT, Extended Tiny Encryption Device (XTEA) are analyzed on the Hardware platform. The Hardware constraints like Area, Frequency, Latency Throughput, and efficiency are evaluated on FPGA devices.