“…Gradually, in the last decades, new strategies and protocols have been developed with the aim of preventing the so-called “lethal triad”, with its components: acidosis, hypothermia and coagulopathy, caused by the great loss of blood ( 4 - 5 ) . In this context, aiming at its prevention and resolution, the Damage Control Surgery (DCS) emerged, which is exclusively used in the operating room and, over the years, it has evolved towards the concept of Damage Control Resuscitation (DCR), encompassing the out-of-hospital and hospital emergency areas ( 2 , 6 - 7 ) . Within the main strategies of the DCR, it is worth highlighting the so-called Massive Transfusion (MT), which consists of the administration of ten or more blood products (red blood cells, plasma and platelets) within the first 24 hours, according to the traditional concept ( 4 , 8 - 9 ) .…”