Le henné Lawsonia inermis L. (Lythraceae)

Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity

“…1) include lapachol 1, extracted as a yellow solid from the tree bark of the Tabebuia species, 13,14 and lawsone 2, obtained from the leaves of Lawsonia inermis (henna) and some trees of the Lythraceae family. 15,16 Both lapachol and lawsone exhibit antimalarial, anti-cancer, antitrypanosomal, antifungal and antibacterial properties that have been used as natural remedies in indigenous communities, 16,17 and both structures can be modied for the development of new drugs that will potentially present selective and efficient mechanisms against malaria, cancer, bacteria and fungi. 8,[18][19][20][21][22][23] Fieser and co-workers, in work that extended over a quarter century, determined the physical and chemical properties of lapachol and lawsone and some synthetic derivatives, in order to evaluate their activity against Plasmodium species.…”

“…1) include lapachol 1 , extracted as a yellow solid from the tree bark of the Tabebuia species, 13,14 and lawsone 2 , obtained from the leaves of Lawsonia inermis (henna) and some trees of the Lythraceae family. 15,16…”