Le papillomavirus : implications carcinologiques et mesures préventives

Bernichon, Emilie; Espenel, Sophie; Méry, Benoîte; Trone, Jane‐Chloé; Rehalia-Blanchard, Amel; He, Yuan Ming; Rancoule, C.; Magné, Nicolas

doi:10.1016/j.lpm.2019.05.019

Cited by 2 publications

(2 citation statements)

References 78 publications

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“…HPVs are bicentennial naked DNA viruses belonging to the family of papillomaviridae. Currently, more than 200 different genotypes have been identified [20]. According to the International Agency for Research on Cancer (AIRC) classifies HPV genotypes 16 and 18 as human carcinogens [21].…”

Section: Introductionmentioning

confidence: 99%

Molecular Genotyping of Human Papillomavirus (HPV) in Hypopharyngeal Cancer

Faye,

Diabira,

Bassoum

et al. 2023

AJMB

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Background: In recent years, head and neck cancers have become common worldwide, ranking sixth in incidence. In 2007, in France the incidence increased by 14,697 including 11,158 among men, which places them in fourth place. The same year, 32,268 patients were hospitalized for this pathology, but 95% are associated with alcohol and tobacco poisoning. Few data exist on these cancers in Africa and Senegal. In recent years, many studies have hypothesized that about 25% of head and neck cancers are associated with high-risk oncogenic human papillomaviruses (HPV) whose role in cervical cancer was already widely established. Objective: To know the prevalence and genotypes of HPV in head and neck cancers, particularly hypopharyngeal cancer. Material and method: This study was carried out on samples of biopsies of hypopharynx cancerous tissue (ulcerative-budding lesion) and healthy oropharyngeal tissue obtained from the ENT department of the Fann hospital, then sent to the Molecular Biology Unit of the Ouakam military hospital (HMO). The nucleic acids extraction was carried out using the standard method of the Zymo research kit "Quick-DNA TM Miniprep Plus kit" https://www.zymoresearch.com/. Molecular HPV detection and genotyping were performed by multiplex RT-PCR with the Seegene Anyplex TM II HPV28 kit Detection on a Biorad CFX96 automaton according to the manufacturer's protocol for the simultaneous genotyping of 28 types of HPV including 19 at High Risk

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Section: Introductionmentioning

confidence: 99%

Molecular Genotyping of Human Papillomavirus (HPV) in Hypopharyngeal Cancer

Faye,

Diabira,

Bassoum

et al. 2023

AJMB

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“…The persistence of high-carcinogenic Papillomavirus infection (HPV genotypes: 16,18,31,33,35,39,45,51,52,58,56,59) leads the cytological and histological alterations of the squamous epithelium cervical [1][2][3]. These alterations are called in several ways either epithelial dysplasia of the cervix or precancerous lesions of the cervix or intraepithelial neoplasia of the uterine cervix [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients

Didier¹,

Véronique²,

Abdon³

et al. 2019

IJCOCR

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The aim of this study is to show the relationship between the index of Papillomavirus infection and the grade of cervical intraepithelial neoplasia as proposed by WHO in Lubumbashi patients. This is a cross-sectional analytical study on cervical biopsies whose histological diagnosis is an intraepithelial neoplasia registered in two Laboratory of Patholoy in Lubumbashi for a period of two years from June 2017 to June 2019. The following results were observed: A total of 41 cases of intraepithelial neoplasia were recorded out of 91 cervical biopsies is 43.2%. Five indices of Human Papillomavirus infection are found in Lubumbashi patients in variable proportions without statistically significant difference; that is the index (5) in 29.27%, the indices (7) and (9) in 21.95% for each index, the index (6) in 17.07% and the index (8) in 9.76%. The three grades of intraepithelial neoplasia proposed by the WHO since 2003 are also found in Lubumbashi patients in varying proportions with no statistically significant difference; 48.78% for grade 3; 36.59% for grade 2 and 14.63% for grade 1. There is no relationship between the HPV infection index and the grade of cervical intraepithelial neoplasia; calculated linear correlation r ^ 2 is equal to 0.00.

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Le papillomavirus : implications carcinologiques et mesures préventives

Cited by 2 publications

References 78 publications

Molecular Genotyping of Human Papillomavirus (HPV) in Hypopharyngeal Cancer

Molecular Genotyping of Human Papillomavirus (HPV) in Hypopharyngeal Cancer

Cervical Intra-Epithelial Neoplasia: Index of Papillomavirus Infection and Histopathological Grade in Lubumbashi Patients

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