Le syndrome ASIA associé aux implants mammaires : lien de causalité ou association fortuite ?

Cordel, E.; Reix, N.; Mathelin, C.

doi:10.1016/j.gofs.2020.06.004

Cited by 2 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 2011 Shoenfeld was first described and Agmon-Levin coined the term Autoimmune/auto-inflammatory/Syndrome Indured by Adjuvants (ASIA) or Shoenfeld syndrome to describe a set of conditions that are the result of an immune response to adjuvants, present with variable latency time and occur as a result of the interaction between genetic and environmental factors, but the idea of an autoimmune-mediated disease was not new, evidence has accumulated that autoimmune symptoms are triggered by exposure to environmental immune-stimulating factors that act as an adjuvant in susceptible individuals [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Asia Syndrome and Breast Implants, Report of A Case and Review of The Literature

Victor Manuel

2023

JCIM

View full text Add to dashboard Cite

Background: Over the past decades, evidence has accumulated that autoimmune symptoms can be triggered by exposure to environmental immunostimulatory factors that act as adjuvants in genetically susceptible individuals, with several unexplained symptoms. Adjuvant-induced autoimmune/autoinflammatory Syndrome (ASIA) was described in 2011 by Shoenfeld and Agmon-Levin and defined the diagnostic criteria. However, the association of this syndrome with silicone breast implants is controversial. Objective: To describe a case of ASIA syndrome in a silicone breast implant carrier and review of the literature. Clinical Case: JKT 36-year-old woman with luminal infiltrating ductal carcinoma; with negative extension studies, a conservative mastectomy of the skin and areola was performed with immediate reconstruction with an implant with a breast prosthesis and hormone therapy; Her follow-up was torpid with fatigue, pain in the arm, depression and sleep disturbances and affected breast skin, without infection. As she did not respond to conservative management, it was decided to remove the prosthesis, resection of the capsule and skin, due to the suspicion of the syndrome. From ASIA, as there was no involvement or persistence of breast cancer, with immediate improvement. Method: Bibliographic review of original articles written in English on cases of ASIA syndromes, associated with silicone breast implants from their description to the present. Results: Until 2019, 126 cases of ASIA syndrome due to silicone breast prostheses and implants were reported. Removal of the prosthesis improves symptoms. Conclusion: ASIA syndrome is recent, it is still considered an evolving concept, it is necessary to identify risk factors for the development of autoimmune phenomena in individuals who will receive some type of adjuvant to prevent cases of this syndrome.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Adjuvants are compounds that, when introduced into the body, develop a specific immune response with high antibody titers against specific pathogens [4]. During the last decade, it became clear that silicone implants act as adjuvants [2,[5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%