Lead Assessment in Biological Samples of Children with Different Gastrointestinal Disorders

Abstract

Lead (Pb) levels have been evaluated in the biological samples of children with different gastrointestinal disorders. Blood, scalp hair, and urine samples of children (of age 4-10 years) complaining about different gastrointestinal disorders were analyzed. For comparison, age matched healthy subjects were also included in this study. Biological samples were digested in a microwave oven prior to Pb determination by graphite furnace atomic absorption spectrometry. Significant differences in Pb profile were found between the diseased and referent children. Elevated Pb contents were observed in case of diseased children than WHO permissible limit, while normal results were obtained for healthy referents. The results were compared with those of healthy children having the same age, socioeconomic status, and residential areas.

Assessment of heavy metal and trace element levels in patients with telogen effluvium

“…Excessive exposure may lead to delayed puberty, neurological disorders, mental retardation, fainting, and even coma. [ 29 30 ] Rossi reported decline in renal functions, hypertension, and peripheral arterial disease even with low blood concentrations of lead. [ 31 ] Abdel Aziz et al .…”

Lead Exposure and Environmental Health

“…Following acute lead exposure, gastrointestinal disorders such as abdominal cramps, diarrhoea with black stools, vomiting and anorexia are most commonly observed in adults at Pb blood concentrations of 100 -200 µg/dL although effects have been observed at concentrations as low as 40 -60 μg/dL (Lockitch, 1993;Shah et al, 2016).…”

Nanoparticles decorated with a Schiff's base for the microextraction of Cd, Pb, Ni, and Co in environmental samples

“…Graphite furnace atomic absorption spectrometry for metallic determination has been widely used with low detection limit . In some cases the determination of trace elements might be a difficult analytical task, normally because of the complex nature of the matrix or lower concentration of these elements, demanding a sensitive instrumental technique and extra sample preparation or preconcentration step . These different sample preparation/preconcentration procedures must be effortless, economical, providing high preconcentration factor and must be within the parameters of green analytical chemistry .…”