“…The systematic synthesis was carried out in only 34 studies that passed the MMAT analysis. The distribution of polluted sources of lead MENA was obtained from Iran (n = 9); Malekirad AA et al[63] 2013, Raissy M [78] 2016, Khatibi-Moghadam H et al [79] 2016, Daneshparvar M et al [89] 2016, Ahmadi M et al [81] 2017, Vahidinia A et al [82] 2018, Soltaninejad K et al [87] 2018, Mayel M et al [90] 2020, Samarghandian S et al [88] 2021; Saudi Arabia (n = 6); Al-Saleh I et al [43] 1996, Al-Saleh I et al [57] 2008, Zolaly MA et al [60] 2012, Ashraf MW et al [61] 2012, Salama AK et al [75] 2016, Chowdhury S et al [83] 2018; Lebanon (n = 5); Nuwayhid I et al [47] 2001, Nuwayhid I et al [51] 2003, Nasreddine L et al [53] 2006, Korfali SI et al [64] 2013, Bassil M et al [84] 2018; Egypt (n = 3); Mortada WI et al [49] 2001, Mandour RA et al [65] 2013, Moawad EM et al [77] 2016; Kuwait (n = 2); Shaltout A et al [41] 1981, Jallad KN et al [56] 2008; Morocco (n = 2); Bouftini S et al [66] 2014, Laamech J et al [68] 2014; Algeria (n = 1); Cher A et al [69] 2014; Iraq (n = 1); Al-Dosky AH et al[59] 2012; Israel (n = 1);Greenberg N et al [76] 2016; Jordan (n = 1); Nusier MK et al[50] 2003; Oman (n = 1); El Tawila M resources, including cosmetics[41,43,51, 56,57, 60,75, 82], socio-economic and cultural[43, 84], and occupational sources that negatively affected both children and adults of both genders[47, 48,49,50, 63,70, 76,77, 88], residential factors that were not limited to paints, but extend to overseas the whole condition of a building (building age, status, ventilation, and whether it near to a generating lead source of pollution) [51, 59, 66, 68, 77, 84, 88], cooking habits[51, 60], oral intake of polluted lead substances[60, 83, 88…”