Lead exposure potentiates predatory attack behavior in the cat

Li, Wenjie; Han, Shenggao; Gregg, Thomas R.; Kemp, Francis W.; Davidow, Amy L.; Louria, Donald B.; Siegel, Allan; Bogden, John D.

doi:10.1016/s0013-9351(02)00083-x

Cited by 34 publications

(20 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies have found an association between subclinical lead toxicosis and delinquent, antisocial, and aggressive behaviors in humans (Sciarillo, 1992;Needleman et al, 1996;Nevin, 2000). Similarly, the development of aggressive behaviors has been documented in domestic dogs and cats with elevated blood lead levels, as well as songbirds (Parus major) exposed to heavy metals (Koh, 1985;Janssens et al, 2003;Li et al, 2003). Pattee and Pain (2003) document an increasing use of lead worldwide and state that ''lead concentrations in many living organisms may be approaching thresholds of toxicity for the adverse effects of lead.''…”

Section: Bridging the Human/animal Dividementioning

confidence: 96%

Lead Poisoning: Using Transdisciplinary Approaches to Solve an Ancient Problem

Pokras

Kneeland

2008

EcoHealth

View full text Add to dashboard Cite

Conservation medicine examines the linkages among the health of people, animals, and the environment. Few issues illustrate this approach better than an examination of lead (Pb) toxicity. Lead is cheap and there is a long tradition of its use. But the toxic effects of Pb have also been recognized for many years. As a result, western societies have eliminated or greatly reduced many traditional uses of Pb, including many paints, gasoline, and solders because of threats to the health of humans and the environment. Legislation in several countries has eliminated the use of lead shot for hunting waterfowl. Despite these advances, a great many Pb products continue to be readily available. For example, wildlife agencies recognize that angling and shooting sports deposit thousands of tons of Pb into the environment each year. In recent years, our knowledge of the lethal and sublethal effects of Pb has grown dramatically. This discussion reviews the effects of lead on wildlife, humans, and domestic animals. It also discusses the importance of bringing together all interest groups to find safe alternatives, to develop new educational and policy initiatives, to eliminate many current uses of Pb, and to clean up existing problems.

show abstract

Section: Bridging the Human/animal Dividementioning

confidence: 96%

Lead Poisoning: Using Transdisciplinary Approaches to Solve an Ancient Problem

Pokras

Kneeland

2008

EcoHealth

View full text Add to dashboard Cite

show abstract

“…Various studies have reported effects of exposure to low doses of lead on agonistic behavior in animal models (Delville, 1999;Holloway & Thor, 1987;Laughlin, Bushnell, & Bowman, 1991;Li et al, 2003;Sloman et al, 2003). For instance, exposure to low doses of lead enhances predatory aggression after cessation of treatment in cats (Li et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

“…For instance, exposure to low doses of lead enhances predatory aggression after cessation of treatment in cats (Li et al, 2003). In rainbow trout, exposure to low doses of lead was associated with a non-significant increase in successful attacks when compared with other trace metals (Sloman et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Lead exposure alters the development of agonistic behavior in golden hamsters

et al. 2005

View full text Add to dashboard Cite

We tested the effects of exposure to different doses of lead acetate (either 0, 25, 100, or 400 ppm) on the development of aggressive behavior in male golden hamsters. Pups were tested for offensive responses across puberty, as they were maturing from play fighting to adult aggression. Our data show a dose-specific effect of lead exposure on the development of aggression during puberty at doses resulting in blood levels well below 20 microg/dl. Animals exposed to 25 ppm lead acetate were faster and performed more than twice as many attacks on intruders by late puberty. They were also twice as likely to initiate adult instead of play-fighting attacks around mid-puberty. These observations were independent of any effect on growth. Thus, exposure to low doses of lead enhanced aggression and accelerated its maturation. As such, our data support the association between exposure to low doses of lead and aggressive behavior in boys.

show abstract

“…2012) can be associated with disturbances in early physical and mental growth and in later intellectual function, and in behavior in children who exposed to lead in fetus period and/or during early childhood (Surkan et al, 2007;Miranda et al, 2007;Kordas et al, 2006;Li et al, 2003;Lanphear et al, 2005). A pooled analysis (Lanphear et al, 2005) predicted a 9.2-point decline in IQ over the range of less than 1-30 mg/dl, two-thirds of this decline (6.2 points) was predicted to occur in the range of less than 1-9.9 mg/dl, with an additional 1.9-point decline between 10 and 19.9 mg/dl, and a 1.1-point decline between 20 and 30 mg/dl.…”

mentioning

confidence: 99%