“…Intracellular mechanism (including efflux, complexation, or biotransformation) and extracellular mechanisms (metals chelated by certain polymeric substances such as metallothionein, siderophore, and extracellular polymeric substances) have been reported in the metal bioremediation process. − Among these detoxification strategies, extracellular polymeric substances (EPS) act as an important, initial defense against metals, and is one of the most important approaches used by microbes to protect cells from metal toxicity, and toxic nanoparticles (NPs). − Many bacteria such as Bacillus sp., Pseudomonas sp., Azotobacter sp., Escherichia coli , Mycobacterium sp., and Halomonas sp. have been frequently reported to produce EPS for bioremediation of metals. ,, Halomonas sp. Exo1, Halomonas elongate , Halomonas BVR1, and Halomonas sp. , were discovered to remediate arsenic, cadmium, lead, and hexavalent chromium in previous studies.…”