“…125,199 Plumbism is more likely if fragments are retained within a joint space, bone, or intervertebral disk, though the latter is less common. 17,89,181,182,[200][201][202] Lead is highly soluble in synovial fluid, thus retained bullets in intra-articular spaces can lead to both local and systemic effects. 147 After dissolving in synovial fluid, the lead can become deposited in subsynovial tissue, resulting in foreign body reactions, arthritis, chronic irritation and inflammation, and absorption into the systemic circulation.…”