2015
DOI: 10.1590/0004-282x20150047
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Lean thinking turns ‘time is brain’ into reality

Abstract: Thrombolysis with intravenous rt-PA is an effective recanalizing treatment for ischemic stroke within 4 and half hours from its onset 1 . It is clear that by providing the treatment earlier the outcome is better with fewer complications 2,3 . A pooled study 4 demonstrated that short stroke-onset-to-treatment time (OTT) with rt-PA had better functional outcomes (modified Rankin Scale, mRS, score of 0 to 1) than patients treated beyond the 90 minute OTT, with odds of 2.8 (95%CI 1.8-4.5) for OTT between 0 to 90 m… Show more

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Cited by 6 publications
(9 citation statements)
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“…For this reason, the entire process should be improved considering together the pre-hospital times (the onset to alarm time and the alarm to door time), and the DNT in further researches [7].…”
Section: Discussionmentioning
confidence: 99%
See 4 more Smart Citations
“…For this reason, the entire process should be improved considering together the pre-hospital times (the onset to alarm time and the alarm to door time), and the DNT in further researches [7].…”
Section: Discussionmentioning
confidence: 99%
“…As stressed by Li ad Johnson [7], rather than requiring that everything goes faster, the entire value stream should be analysed, in order to eliminate the activities that not add value.…”
Section: Lean Management To Improve Stroke Carementioning
confidence: 99%
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