The business, management, and entrepreneurship (BME) education provided by universities is believed to influence the way in which organisations are managed in the business world. In recent decades, it has been criticised for its focus on profit and short-term goals, while new approaches inspired by the humanities, particularly religious and spiritual traditions, have been proposed. Although research in this area is growing, it is scattered. In this study, we systematically review the existing literature to deepen our understanding of this emergent stream of research. From a sample of 216 papers, 51 articles from 1996 to 2023, selected from the Web of Science and Scopus databases, are analysed. Overall, the findings highlight that the literature on this topic is predominantly theoretical and suggest that some of the wisdom embedded in religion and spirituality might be considered to inform different discussions in BME courses, with a prominent application of sacred and ancient texts in the teaching of business ethics. Future research avenues are discussed in relation to a variety of themes and pedagogical and empirical approaches that can benefit scholars and advance this area of study.