Lymph-edema of lower limbs is one of the common complications of gynecologic cancer patients. Once lymph-edema of lower extremities appears after treatment, it is difficult to cure, which seriously affects the quality of treatment of patients. Lymph-edema early detection and timely intervention is important. In order to prevent and treat the lymph-edema of lower limbs in patients with gynecological malignancies in the early stage, this paper uses the computer-aided diagnosis method to scan the lower limbs of patients with gynecological malignant tumors by using CT imaging technology, and identify the location of lesions in patients with gynecological malignant tumors, and carry out image enhancement and denoising on the scanned CT images to mark the lesion sites. The incidence rate of incidence of lymph-edema in lower extremities was analyzed according to the patients' basic characteristics. The influence of different treatment methods on the incidence rate of lymph-edema and the incidence rate of lymph-edema in different stages of gynecologic malignancies were also analyzed. Finally, a drop of congestive therapy based on the research literature, three drugs therapy and surgical therapy for lower extremity lymph-edema intervention programs, through the patient's body recovery, lower limb swelling analysis of these three methods to effect the lower extremity lymph-edema, for patients to find a suitable intervention programs. The final results showed that the number of patients between the ages of 40-49 and 60-69 were the largest, reaching 427 and 417 respectively, and the heavier the patient, the higher the incidence. Radiotherapy, chemotherapy and pelvic lymph node dissection resulted in 89.73%, 89.76% and 86.96% of patients with lower limb lymph-edema, which is one of the risk factors for lower limb lymph-edema. Among the three intervention programs for lymph-edema of the lower limbs, decongestant therapy has a slower treatment speed but low cost and no side effects. Drug treatment can only be applied to some patients, and surgical treatment has good results but high cost.