Leber′s miliary aneurysms

Abstract

Leber's disease is a form of primary retinal telangiectasia characterized by the presence of abnormalities in the retinal vasculature. It is an idiopathic, unilateral condition with male predilection. It is not associated with any other systemic or ocular disease. The disease has a very slow progression and can be complicated by vascular dilatations, neovascularizations, thromboses, retrovitreal hemorrhages, and macular changes. We present a case of Leber's miliary aneurysms in an asymptomatic 22-year-old male patient. His fundus examination showed aneurysmal dilatations with lipid exudation. Intravenous fluorescein angiography showed early and late leakage as well as capillary dropout with late hypofluorescence. In this case, the patient was treated with laser photocoagulation of the retina.

Idiopathic Peripheral Retinal Telangiectasia in Adults: A Case Series and Literature Review

“…Idiopathic, nonhereditary aneurysmal retinal telangiectasia associated with intraretinal exudation and frequent exudative retinal detachment, occurring in patients aged a few months to seven decades with the peak in the first decade of life [2] Leber miliary aneurysms A milder variant of Coats disease, usually occurring in young adults and located at the retinal periphery [7][8][9] Idiopathic retinal telangiectasia A descriptive name for a Coats disease MACTEL type 1…”

“…Its severe form (referred to as Coats disease) and milder form (sometimes termed Leber miliary aneurysms) that commonly present in adults, were initially described as separate entities [ 7 ]. Now, they are considered to be variable expressions of the same disease This explains its adult onset, as milder forms often stay asymptomatic for a long period of time [ 8 , 9 ]. Less severe forms of Coats disease fall into category 1, 2A and 2 B of the Shields classification commonly used to describe the stages of this disease [ 10 ].…”