Lecithin doped electrospun poly(lactic acid)-thermoplastic polyurethane fibers for hepatocyte viability improvement

Liu, Xiang; Zhou, Lingtong; Heng, Peng; Xiao, Jingcheng; Lv, Junping; Zhang, Qingmiao; Hickey, Michael E.; Tu, Qin; Wang, Jinyi

doi:10.1016/j.colsurfb.2018.09.069

Cited by 35 publications

(18 citation statements)

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“…The successful production of neurotrophic growth factor allowed PC12 cells to have a sustained neurite outgrowth. Liu and co-workers [160] focused on the in vitro growth of hepatocytes and saw that a lecithin modified PLA-polyurethane composite allowed HePG2 cells to grow more sustainably compared to growth in culture plates alone. A more peculiar approach was reported by Paolini and colleagues [161], wherein a PLA polymer was coated with a polyamidoamine bound miRNA to transfect genes to plated HeLa cells.…”

Section: Bioscaffolds For Cell Cultivation In Vitromentioning

confidence: 99%

Recent Advances in Bioplastics: Application and Biodegradation

et al. 2020

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The success of oil-based plastics and the continued growth of production and utilisation can be attributed to their cost, durability, strength to weight ratio, and eight contributions to the ease of everyday life. However, their mainly single use, durability and recalcitrant nature have led to a substantial increase of plastics as a fraction of municipal solid waste. The need to substitute single use products that are not easy to collect has inspired a lot of research towards finding sustainable replacements for oil-based plastics. In addition, specific physicochemical, biological, and degradation properties of biodegradable polymers have made them attractive materials for biomedical applications. This review summarises the advances in drug delivery systems, specifically design of nanoparticles based on the biodegradable polymers. We also discuss the research performed in the area of biophotonics and challenges and opportunities brought by the design and application of biodegradable polymers in tissue engineering. We then discuss state-of-the-art research in the design and application of biodegradable polymers in packaging and emphasise the advances in smart packaging development. Finally, we provide an overview of the biodegradation of these polymers and composites in managed and unmanaged environments.

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Section: Bioscaffolds For Cell Cultivation In Vitromentioning

confidence: 99%

Recent Advances in Bioplastics: Application and Biodegradation

et al. 2020

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“…PVA-DES-honey/ASA nanobers were prepared by electrospinning according to reported procedures. [21][22][23] An electrospinning solution of PVA (10.5%, w/v), an electrospinning solution of PVA (9%, w/v) and DES (5%, w/v), an electrospinning solution of PVA (9%, w/v), DES (5%, w/v) and ASA (5%, w/v), and an electrospinning solution of PVA (8%, w/v), DES (5%, w/v) and honey (5%, w/v) were sprayed from a 10 mL plastic syringe at a rate of 0.75 mL h À1 . A voltage of 23 kV is applied to the needle, where the positive high voltage was 18 kV and the negative high voltage was 5 kV.…”

Section: Methodsmentioning

confidence: 99%

“…8,24 2.2.5 Tensile properties. Mechanical properties of the PVA, PVA-DES, PVA-DES-honey, PVA-DES-ASA nanobers were investigated according to reported procedures, 22,26 using a universal tensile testing machine (DDL10, EDC-controller, Germany and China) with a crosshead rate of 5 mm min À1 . The sample was stabilized on a frame with a gauge length of 10 mm, and equipped with a 100 N load cell.…”

Section: Methodsmentioning

confidence: 99%

Fabrication of green poly(vinyl alcohol) nanofibers using natural deep eutectic solvent for fast-dissolving drug delivery

et al. 2021

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“…The addition of the thermoplastic material PU improves the brittleness of PLA, and further promotes the growth and proliferation of hepatocytes. 52 In addition, materials for bone tissue, cartilage tissue and vascular transplantation can also be prepared. da Silva et al 53 used PLA and PVA as materials to prepare the nanober scaffold with a core-shell structure by electrospinning as the carrier of the BMP-2 protein, and applied to the recovery of alveolar bone tissue.…”

Section: Tissue Engineeringmentioning

confidence: 99%