The research aims to examine the influence of media and information literacy (MIL) skills on the individual work performance of academic staff of colleges of education. Researchers discovered that many educational professionals need more MIL skills to support their job performance. This set of skills required for effective research and information use is insufficient and impedes lifelong learning. Based on the review of related literature, a 50-item questionnaire was constructed. The study population is 3,200 from nine public education colleges in southeast Nigeria. A representative sample for the study is 344, derived from the Sample Size Calculator by Raosoft Inc. A proportionate stratified random sampling technique was employed to identify a representative sample for the study. To ensure data validity, reliability, and normality, the research instrument was pre-tested by experts/scholars. A pilot test was conducted, and thirty-nine academic staff participated. A quantitative survey method was used, employing SPSS to analyze collected data. Findings revealed that all items have reliability coefficients above 0.70 except for need skills, locate skills, and analyze skills with 0.566, 0.531, and 0.545 values. The study recommends that management should pay close attention to the MIL skills of their staff to optimize individual work performance.