Left adrenal gland metastasis of breast invasive ductal carcinoma: A case report

Abstract

Abstract. The majority of the metastatic lesions of the adrenal gland normally originate from lung cancer, colon malignant tumor, renal cell carcinoma and melanoma. However, adrenal gland metastasis that metastasize from breast invasive ductal carcinoma are extremely rare. The present study reported a rare case of left adrenal gland metastasis in a 35-year-old female who was diagnosed as breast carcinoma 5 years ago with a mass located on the left adrenal gland, which was detected during a routine examination. The patient was asymptomatic and adrenal gland computed tomography revealed a mass in the left adrenal gland. Definitive preoperative diagnosis failed to be established. Left adrenal gland laparoscopic adrenalectomy was performed and the diagnosis of adrenal gland metastasis of breast invasive ductal carcinoma was confirmed by pathological and immunohistochemical examination. The patient remained in good condition by the time of writing.

Isolated right adrenal metastasis from an invasive ductal breast carcinoma.

“…In our case immunoassaying confirmed the breast origin. Patients with adrenal metastasis usually are asymptomatic and start to express suprarenal gland disfunction only when most of the adrenal gland is replaced or destroyed [7,8]. Our patient underwent Laparoscopic Right Adrenalectomy which was converted to open due to the large size of the tumor.…”

Recurrent Invasive Ductal Breast Carcinoma Presenting as Primary Adrenal Insufficiency with Adrenal Crisis

“…In a study of metastatic patterns of breast cancer, Borst et al (8) reported that in a group of 2,246 patients with invasive ductal carcinoma, there were no observations of adrenal gland metastasis. This occurrence has only been demonstrated in prior case reports (3,6,(9)(10)(11)(12). Adrenal involvement usually occurs in the setting of widespread metastasis with solitary adrenal metastasis exceedingly rare (2).…”

Solitary Adrenal Metastases from Breast Invasive Ductal Carcinoma

“…From what we know, the first published case was in 2010 by Xiao-Jiao Liu et al in "Solitary adrenal metastasis from invasive ductal breast cancer: an uncommon finding" (5). We managed to find only six published cases of adrenal metastases from invasive carcinoma of no special type untill the time of writing (3,6,7,8,9).…”

“…Only few of the patients may have suprarenal gland disfunction if most of the adrenal gland is replaced or destroyed (9). Compared to metastases, primary adrenal glands malignancies such as adrenocortical carcinomas frequently secrete hormone excessively, causing certain relative symptoms (10).…”