Left and right ventricle assessment with Cardiac CT: validation study vs. Cardiac MR

Abstract

ObjectivesTo compare Magnetic Resonance (MR) and Computed Tomography (CT) for the assessment of left (LV) and right (RV) ventricular functional parameters.MethodsSeventy nine patients underwent both Cardiac CT and Cardiac MR. Images were acquired using short axis (SAX) reconstructions for CT and 2D cine b-SSFP (balanced-steady state free precession) SAX sequence for MR, and evaluated using dedicated software.ResultsCT and MR images showed good agreement: LV EF (Ejection Fraction) (52 ± 14% for CT vs. 52 ± 14% for MR; r = 0.73; p > 0.05); RV EF (47 ± 12% for CT vs. 47 ± 12% for MR; r = 0.74; p > 0.05); LV EDV (End Diastolic Volume) (74 ± 21 ml/m² for CT vs. 76 ± 25 ml/m² for MR; r = 0.59; p > 0.05); RV EDV (84 ± 25 ml/m² for CT vs. 80 ± 23 ml/m² for MR; r = 0.58; p > 0.05); LV ESV (End Systolic Volume)(37 ± 19 ml/m² for CT vs. 38 ± 23 ml/m² for MR; r = 0.76; p > 0.05); RV ESV (46 ± 21 ml/m² for CT vs. 43 ± 18 ml/m² for MR; r = 0.70; p > 0.05). Intra- and inter-observer variability were good, and the performance of CT was maintained for different EF subgroups.ConclusionsCardiac CT provides accurate and reproducible LV and RV volume parameters compared with MR, and can be considered as a reliable alternative for patients who are not suitable to undergo MR.Key Points• Cardiac-CT is able to provide Left and Right Ventricular function.• Cardiac-CT is accurate as MR for LV and RV volume assessment.• Cardiac-CT can provide accurate evaluation of coronary arteries and LV and RV function.Electronic supplementary materialThe online version of this article (doi:10.1007/s00330-011-2345-6) contains supplementary material, which is available to authorized users.

Impact of age and sex on left ventricular function determined by coronary computed tomographic angiography: results from the prospective multicentre CONFIRM study

“…However, previous studies have demonstrated high accuracy and a tight concordance of LVEF values obtained by cardiac CT with those provided by CMR. 44,45 In addition, our results correlate well with previously published functional LV values for CMR and echocardiography. 46,47 Third, our results are based on a population that has been referred for cardiac CT.…”

Pericardial Disease: Value of CT and MR Imaging

“…Moreover, delayed (or late) gadolinium-enhanced MR imaging is useful for the detection of pericardial inflammation and for monitoring the effects of medical (anti-inflammatory) treatment (20,21). Cardiac CT with multidetector scanners and electrocardiographically (ECG) synchronized data acquisition allows an accurate assessment of the coronary arteries and the remainder of the heart and pericardium, including functional cardiac analysis (22)(23)(24)(25).…”

Cardiovascular Function and Treatment in β-Thalassemia Major

“…There are few data on the use of cardiac computed tomography in TM, but it is a fast technique to assess cardiac function, 111 and liver attenuation correlates with MR-derived liver iron concentration, but only at moderately to severely increased levels of iron in the liver. 112 No significant data exist on measurement of cardiac iron by computed tomography.…”