Left Atrial Volume to Predict the Recurrence of Atrial Fibrillation in Patients Treated with Catheter Ablation

Desai, Dev; Suthar, Nilay

doi:10.2478/jce-2023-0008

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Furthermore, the multivariate analysis demonstrated that LAVI has a positive correlation with AF recurrence. These results agree with previous studies, which reported a significantly higher probability of relapse in patients with large LA volumes assessed by CCTA [ 25 , 32 ].…”

Section: Discussionsupporting

confidence: 93%

Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study

Bordi,

Benedek,

Kovács

et al. 2023

Life

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Background: Identification of predictors for atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) can lead to better long-term results. Our aim was to investigate the association between novel CT imaging markers reflecting the severity of coronary atherosclerosis and the risk of recurrence following PVI. Methods: This study included 80 patients with paroxysmal/persistent AF who underwent PVI. The patients were divided into two groups: Group 1–23 patients with recurrence and Group 2–57 patients without recurrence. Results: Patients with recurrence presented with a more enlarged left atrial diameter and reduced left ventricle EF, as assessed by echocardiography. Elevated calcium scores and right coronary artery (RCA) stenosis were correlated with a higher risk of AF recurrence (25.38 ± 4.1% vs. 9.76 ± 2.32%, p = 0.001). Patients with AF recurrence presented a higher left atrial volume index (LAVI) (61.38 ± 11.12 mm3/m2 vs. 46.34 ± 12.27 mm3/m2, p < 0.0001). The bi-atrial volume index (BAVI) was similarly higher in the AF recurrence group (98.23 ± 14.44 mm3/m2 vs. 76.48 ± 17.61 mm3/m2, p < 0.0001). Increased EAT volumes located around the LA (EAT-LA) were correlated with recurrence (25.55 ± 6.37 vs. 15.54 ± 8.44, p < 0.0001). Conclusions: RCA stenosis, together with atrial volumes and EAT-AS evaluated by CCTA, is associated with the risk of AF recurrence following PVI.

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Section: Discussionsupporting

confidence: 93%

Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study

Bordi,

Benedek,

Kovács

et al. 2023

Life

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“…The significant enlargement of the left atrium in AF patients underscores the well-established association between left atrial size and AF. Although there is some debate about whether a dilated atrium can predict post-ablation AF recurrence, enlargement is a recognized marker of AF and its severity [ 18 , 19 , 20 ]. The higher CCS in patients without AF and the greater severity of lesions in the LCX and RCA highlight a complex interplay between AF and CAD.…”

Section: Discussionmentioning

confidence: 99%

“…The higher CCS in patients without AF and the greater severity of lesions in the LCX and RCA highlight a complex interplay between AF and CAD. This relationship is emphasized by the shared risk factors and common pathophysiological characteristics between AF and CAD, where systemic inflammation plays a crucial role in both conditions [ 20 ]. It is also important to note the effectiveness of PCAT-FAI, as determined by CCTA, in detecting inflammation in PCAT [ 21 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

CT-Assessment of Epicardial Fat Identifies Increased Inflammation at the Level of the Left Coronary Circulation in Patients with Atrial Fibrillation

Gerculy,

Benedek,

Kovács

et al. 2024

JCM

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Background: Atrial fibrillation (AF) can often be triggered by an inflammatory substrate. Perivascular inflammation may be assessed nowadays using coronary computed tomography angiography (CCTA) imaging. The new pericoronary fat attenuation index (FAI HU) and the FAI Score have prognostic value for predicting future cardiovascular events. Our purpose was to investigate the correlation between pericoronary fat inflammation and the presence of AF among patients with coronary artery disease. Patients and methods: Eighty-one patients (mean age 64.75 ± 7.84 years) who underwent 128-slice CCTA were included in this study and divided into two groups: group 1 comprised thirty-six patients with documented AF and group 2 comprised forty-five patients without a known history of AF. Results: There were no significant differences in the absolute value of fat attenuation between the study groups (p > 0.05). However, the mean FAI Score was significantly higher in patients with AF (15.53 ± 10.29 vs. 11.09 ± 6.70, p < 0.05). Regional analysis of coronary inflammation indicated a higher level of this process, especially at the level of the left anterior descending artery (13.17 ± 7.91 in group 1 vs. 8.80 ± 4.75 in group 2, p = 0.008). Conclusions: Patients with AF present a higher level of perivascular inflammation, especially in the region of the left coronary circulation, and this seems to be associated with a higher risk of AF development.

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Exercise and Atrial Fibrillation: Friends or Foes?

Cristina Daha,

Bădilă

2024

Atrial Fibrillation - Current Management and Practice [Working Title]

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Atrial fibrillation (AF) has an increasing prevalence and is foreseen as a true epidemic in the coming years. Moreover, the presence of AF has a huge impact on the everyday quality of life and also on the prognosis of the affected patients. Lifestyle interventions including exercise-based interventions are an essential component of the guideline-driven Atrial Fibrillation Better Care (ABC) pathway. Nevertheless, physicians are not extensively using this extremely valuable tool in AF prevention, both primary and secondary prevention, because of a lack of knowledge and fear of inducing harm. On the other hand, patients are afraid of experiencing symptoms and lower their physical activity to a “safe” minimum. Therefore, shedding light on this important topic is extremely important. The aim of the chapter is to highlight the bivalent and somehow counterintuitive relationship between exercise and atrial fibrillation with a special focus on exercise prescription in everyday AF patients.

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Left Atrial Volume to Predict the Recurrence of Atrial Fibrillation in Patients Treated with Catheter Ablation

Cited by 3 publications

References 11 publications

Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study

Association of Atrial Fibrillation Recurrence with Right Coronary Atherosclerosis and Increased Left Arterial Epicardial Fat Following Catheter Ablation—Results of a Multimodality Study

CT-Assessment of Epicardial Fat Identifies Increased Inflammation at the Level of the Left Coronary Circulation in Patients with Atrial Fibrillation

Exercise and Atrial Fibrillation: Friends or Foes?

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