Left hemisphere plasticity and aphasia recovery

Fridriksson, Julius; Richardson, Jessica D.; Fillmore, Paul; Cai, Bo

doi:10.1016/j.neuroimage.2011.12.057

Cited by 180 publications

(186 citation statements)

References 68 publications

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“…With respect to recovery, some studies demonstrate that right hemisphere compensation is responsible for improvement in language over time (e.g., Rosen et al, 2000), while others show perilesional activity or involvement of other undamaged areas in the lesioned hemisphere (e.g., Fridriksson, Richardson, Fillmore, & Cai, 2012). Most studies reveal a mixture of these patterns (for reviews, see Crinion & Leff, 2007;Thompson & den Ouden, 2008).…”

Section: Functional Neuroimagingmentioning

confidence: 99%

What Do Language Disorders Reveal about Brain–Language Relationships? From Classic Models to Network Approaches

Dronkers

Ivanova

Baldo

2017

J Int Neuropsychol Soc

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Studies of language disorders have shaped our understanding of brain-language relationships over the last two centuries. This article provides a review of this research and how our thinking has changed over the years regarding how the brain processes language. In the 19th century, a series of famous case studies linked distinct speech and language functions to specific portions of the left hemisphere of the brain, regions that later came to be known as Broca's and Wernicke's areas. One hundred years later, the emergence of new brain imaging tools allowed for the visualization of brain injuries in vivo that ushered in a new era of brain-behavior research and greatly expanded our understanding of the neural processes of language. Toward the end of the 20th century, sophisticated neuroimaging approaches allowed for the visualization of both structural and functional brain activity associated with language processing in both healthy individuals and in those with language disturbance. More recently, language is thought to be mediated by a much broader expanse of neural networks that covers a large number of cortical and subcortical regions and their interconnecting fiber pathways. Injury to both grey and white matter has been seen to affect the complexities of language in unique ways that have altered how we think about brain-language relationships. The findings that support this paradigm shift are described here along with the methodologies that helped to discover them, with some final thoughts on future directions, techniques, and treatment interventions for those with communication impairments. (JINS, 2017, 23, 741-754)

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Section: Functional Neuroimagingmentioning

confidence: 99%

What Do Language Disorders Reveal about Brain–Language Relationships? From Classic Models to Network Approaches

Dronkers

Ivanova

Baldo

2017

J Int Neuropsychol Soc

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“…In studies of Hamilton et al 37 and Martin et al 38 , the stimulation protocols were applied in three subjects (one and two, respectively) with chronic aphasia (more than a year). The results were significant for the improvement of the language in the case of the study in 2010 and for one of the participants of the study in 2009, indicating that the same protocol may not produce the improvement of language for all patients, depending mainly of injured areas, issue discussed by Martin, et al 38 , and indicated in the Sarasso et al 18 , Fridriksson et al 21 and Fridriksson et al 22 studies. Jung et al 29 and Naeser et al 39 aimed to study the rehabilitation of speech in a case of Global Aphasia with the right dominant hemisphere, and non-fluent Aphasia associated with sleep apnea.…”

Section: Treatments With Repetitive Trans Cranial Electric Stimulatiomentioning

confidence: 78%

“…Among the studies whose objective was to investigate the recovery of a specific language ability, two examined the relationship between the improvement in the ability of naming, the cerebral activation 22 and the extension of the lesion 23 . Both studies involved 20 participants on average, with fluent and non-fluent aphasia, and used the techniques of semantic, phonological and gestures facilitators, which were compared among them.…”

Section: E Assessment Of Methodological Rigormentioning

confidence: 99%

Intervenções em afasia: uma revisão integrativa

Fontanesi

Schmidt

2016

Rev. CEFAC

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This review aims to identify, evaluate and discuss articles of aphasia interventions and therapeutic advances, published in free access scientific journals in the last five years. An integrative review was performed on databases SciELO, LILACS, CAPES and PubMed, with the descriptors in English and Portuguese: aphasia, rehabilitation and treatment. Inclusion criteria were as follows: articles describing aphasia treatment or rehabilitation stories, published in English or Portuguese. I was found 96 studies that met the criteria that were read and analyzed according to an integrative review protocol, then categorized resulting in 26 articles included. I t was observed a predominance of quantitative studies. Several studies that tested therapies showed positive results, confirming that aphasia is a condition that responds to a wide variety of treatments. Investigations focused on brain activation demonstrated significant correlations between patients' improvement and brain activation of language areas. It was found that aphasia treatments description did not indicate a superior therapeutic approach compared to another. Most studies did not present good degree of external general, indicating the need for controlled studies with more representative samples. The current literature should support the actions of the professionals, but these should be alert to the characteristics and limitations of the protocols tested. Keywords: Aphasia; /therapy; Rehabilitation; Review RESUMO O objetivo desta revisão foi identificar, avaliar e discutir artigos sobre intervenções e avanços terapêuticos em afasia, publicados periódicos científicos nos últimos cinco anos, em plataformas de livre acesso aos profissionais. Foi realizada uma revisão integrativa nas bases de dados SciELO, LILACS, Periódicos Capes e PubMed, com os descritores em português e inglês: afasia, reabilitação e tratamento. Foram incluí-dos artigos que descrevessem tratamentos para afasia ou histórias de reabilitação, publicados em inglês ou português. Os estudos que atenderam aos critérios foram lidos e analisados segundo instrumento para revisão integrativa, e posteriormente categorizada. Dos 96 artigos levantados 26 foram incluídos na revisão. Houve predominância de estudos quantitativos. De modo geral, diversas pesquisas que testavam terapias mostraram resultados positivos, confirmando que a afasia é uma condição que responde a uma ampla variedade de tratamentos. Nos estudos cujo foco foi a ativação cerebral, foram encontradas correlações importantes entre a melhora dos pacientes e a ativação de áreas cerebrais relacionadas à linguagem. A partir dos resultados, verificou-se que os tratamentos para afasia descritos não indicam a superioridade de uma abordagem terapêutica sobre outra. A maioria dos estudos revisados não apresentava bom grau de generalidade externa, indicando a necessidade de estudos controlados com amostras mais representativas. A literatura atualizada deve fundamentar as ações dos profissionais, porém esses devem estar atentos às característ...

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“…It has been previously suggested that the degree of impairment and plasticity in the white matter fiber tracts relevant to language processing is also of great importance in predicting the recovery of language function (Naeser, Palumbo, Helm-Estabrooks, Stiassny-Eder, & Albert, 1989;Schlaug, Marchina, & Norton, 2009). Besides, language and speech therapy can lead to the reorganization of language neural networks accounting for brain plasticity in stroke survivors (Fridriksson, Richardson, Fillmore, & Cai, 2012) even at the chronic phase (Meinzer et al, 2004). However, the information of language and speech therapy was not available in most cases reported in the present study and thus, we could not address its effects on language recovery.…”

Section: Discussionmentioning

confidence: 99%

Language recovery and evidence of residual deficits after nonthalamic subcortical stroke: A 1 year follow-up study

Peñaloza

Rodrı́guez-Fornells

Rubio

et al. 2014

Journal of Neurolinguistics

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a b s t r a c tA variety of language disturbances including aphasia have been described after subcortical stroke but less is known about the factors that influence the long-term recovery of stroke-induced language dysfunction. We prospectively examined the role of the affected hemisphere and the lesion site in the occurrence and recovery of language deficits in nonthalamic subcortical stroke. Forty patients with unilateral basal ganglia stroke underwent language assessment within 1 week, 3 months and 1 year after stroke. Disturbances in at least one language domain were observed in 35 patients during the first week post stroke including aphasia diagnosed in 11 patients. Importantly, the appearance of deficits after stroke onset and the improvement of language function were not determined by the site of subcortical lesion, but instead were critically influenced by the affected hemisphere. In fact, the language impairments following left and right basal ganglia stroke mirrored the language dysfunction observed after cortical lesions * Corresponding authors. Tel./fax: þ34 934020993.E-mail addresses: cpenaloza@idibell.cat, claudia_penaloza@hotmail.com (C. Peñaloza), mjuncadella@bellvitgehospital.cat (M. Juncadella). Journal of Neurolinguistics 32 (2014) 16e30 in the same hemisphere. A significant overall language improvement was observed at 3 months after stroke, although residual deficits in language executive function were the most commonly observed impairment at 1 year follow-up. Although a substantial improvement of language function can be expected after nonthalamic subcortical stroke, our findings suggest that language recovery may not be fully achieved at 1 year post stroke. Contents lists available at ScienceDirect Journal of Neurolinguistics

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Left hemisphere plasticity and aphasia recovery

Cited by 180 publications

References 68 publications

What Do Language Disorders Reveal about Brain–Language Relationships? From Classic Models to Network Approaches

What Do Language Disorders Reveal about Brain–Language Relationships? From Classic Models to Network Approaches

Intervenções em afasia: uma revisão integrativa

Language recovery and evidence of residual deficits after nonthalamic subcortical stroke: A 1 year follow-up study

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